原位制备过氧化氢实现尼龙单体的绿色合成  

Highly Efficient Catalytic Production of Oximes from Ketones Using in Situ–Generated H_(2)O_(2)

作　　者：彭卿[1] 李亚栋[1] Qing Peng;Yadong Li(College of Chemistry,Tsinghua University,Beijing 100084,China)

机构地区：[1]清华大学化学系,北京100084

出　　处：《化学进展》2022年第5期1015-1016,共2页Progress in Chemistry

摘　　要：过氧化氢(H_(2)O_(2))具有较合适的氧化能力,而且其反应产物为水,非常适合作为一种环境友好的选择性氧化剂应用于绿色化学合成。例如,工业上利用钛硅分子筛催化过氧化氢氨氧化环己酮,制备尼龙6的单体环己酮肟,可以大幅度简化生产工艺,在获得高转化率和高选择性的同时,极大地减少了低价值副产物和废弃物的产生,使得整个过程更加绿色经济。目前,全球年产超过600万吨环己酮肟,其中70%以上都使用过氧化氢氨氧化法制备[1]。By using supported gold-palladium alloyed nanoparticles in conjunction with a titanium silicate-1(TS-1)catalyst,H_(2)O_(2)can be generated in situ as needed,producing cyclohexanone oxime with>95%selectivity,comparable to the current industrial route.The ammoximation of several additional simple ketones is also demonstrated.Our approach eliminates the need to transport and store highly concentrated,stabilized H_(2)O_(2),potentially achieving substantial environmental and economic savings.This approach could form the basis of an alternative route to numerous chemical transformations that are currently dependent on a combination of preformed H_(2)O_(2) and TS-1,while allowing for considerable process intensification.

关 键 词：环己酮肟 过氧化氢 高选择性 氨氧化 原位制备 环境友好 钛硅分子筛 绿色合成 

分 类 号：O624.42[理学—有机化学]