水相识别分子印迹聚合物在样品预处理中的应用  

The Application of Aqueous Recognition Molecularly Imprinted Polymers in Sample Pretreatment

作　　者：周天瑜 王彦博 赵翌琳 李洪吉 刘春波[1,2,3] 车广波 Tianyu Zhou;Yanbo Wang;Yilin Zhao;Hongji Li;Chunbo Liu;Guangbo Che(Key Laboratory of Preparation and Application of Environmental Friendly Materials,Ministry of Education,Jilin Normal University,Changchun 130103,China;College of Environmental Science and Engineering,Jilin Normal University,Siping 136000,China;Key Laboratory of Environmental Materials and Pollution Control,The Education Department of Jilin Province,Jilin Normal University,Siping 136000,China;College of Chemistry,Jilin Normal University,Siping 136000,China;Jilin Qingtian Environmental Protection Technology Processing Center Co.,Ltd,Changchun 130519,China)

机构地区：[1]吉林师范大学环境友好材料制备与应用教育部重点实验室,长春130103 [2]吉林师范大学环境科学与工程学院,四平136000 [3]吉林师范大学吉林省高校环境材料与污染控制重点实验室,四平136000 [4]吉林师范大学化学学院,四平136000 [5]吉林省晴天环保科技处理中心有限公司,长春130519

出　　处：《化学进展》2022年第5期1124-1135,共12页Progress in Chemistry

基　　金：国家自然科学基金项目(No.22004047,21906062);吉林省科技厅项目(No.20180623042TC);吉林省人力资源和社会保障厅项目(No.2017956);吉林省生态环境厅项目(No.2019-01-07);吉林省发展和改革委员会项目(No.2021C036-7);吉林省教育厅项目(No.JJKH20200427KJ)资助。

摘　　要：分子印迹聚合物(MIPs)是模拟抗原-抗体识别机制,人工构筑的对目标物具有专一识别性的材料,构建具有优异水相识别能力的MIPs是分子印迹领域长期面临的挑战。近年来水相识别MIPs以其优异的抗基质干扰和水中识别能力,引起了分析化学家、材料学家和环境学家的广泛关注。本文综述了近年来水相识别MIPs在样品预处理中的应用研究。首先,简要介绍了MIPs的构筑原理、优势及面临水相识别困难的挑战。其次,介绍了样品前处理技术及其重要性。再次,结合各类新兴材料和MIPs制备技术,从样品前处理技术的角度(包括固相萃取、分散固相萃取、磁固相萃取、固相微萃取、管尖固相萃取和搅拌棒吸附萃取)全面总结了水相识别MIPs在含水样品分析中的应用,并结合材料性能和分析参数讨论了各类方法的分析优势。最后,分别从水相识别MIPs构建和预处理两方面提出了该领域面临的挑战和未来的发展趋势。Molecularly imprinted polymers(MIPs)are artificially constructed materials that mimic the recognition mechanism of antigens and antibodies.The construction of MIPs with excellent aqueous recognition capacity has been a long-term challenge in molecular imprinting fields.In recent years,aqueous recognition MIPs have attracted extensive attention from analytical chemists,materials scientists and environmentalists due to their excellent aqueous recognition and anti-matrix interference ability.In this article,we summarize the preparation and application of aqueous recognition MIPs in sample pretreatment in recent years.Firstly,the construction principles,advantages of MIPs and challenges of MIPs in aqueous recognition are briefly introduced.Secondly,sample pretreatment and its importance are introduced.Thirdly,combined with various emerging materials and preparation techniques of MIPs,the application of aqueous recognition MIPs in sample pretreatment is comprehensively summarized from the perspective of sample pretreatment techniques involving solid phase extraction,dispersive solid phase extraction,magnetic solid phase extraction,solid phase microextraction,pipette tip solid phase extraction and stir bar adsorption extraction.Meanwhile,the advantages of various methods in the analysis of water environment samples are discussed in combination with material properties and analytical parameters.Finally,the challenges and future development trends in this field are presented from perspectives of the construction of aqueous recognition MIPs and sample pretreatment.

关 键 词：分子印迹聚合物 水相识别 样品预处理 亲水 水兼容 

分 类 号：O631.3[理学—高分子化学] O658.2[理学—化学]