HRM技术在非人源性法医物证检测中的应用  

Application of HRM analysis in non-human forensic evidence detection

作　　者：张卫萍 阿地来·吐尔逊 冯巍[1] 秦豪杰[1] 莫耀南[1] 翟仙敦[1] Zhang Weiping;Adilai Tuerxun;Feng Wei;Qin Haojie;Mo Yaonan;Zhai Xiandun(School of Forensic Medicine,Henan University of Science and Technology,Luoyang 471023,China)

机构地区：[1]河南科技大学法医学院,河南洛阳471023

出　　处：《中国法医学杂志》2022年第3期243-245,250,共4页Chinese Journal of Forensic Medicine

基　　金：河南省高等学校重点科研项目基础研究计划(18B310002);洛阳市法医技术鉴定重点实验室(11550002);河南省科技攻关计划项目(182102310560)。

摘　　要：高分辨率熔解曲线(High Resolution Melting,HRM)是为检测核酸序列中的遗传变异而发展起来的一种后PCR方法,因简单高效、准确可靠,受到越来越多的法医科研人员关注。本文概述了HRM技术的原理、优势,综述了其在法医非人源性物证鉴定中的应用进展,并对其前景进行展望。High Resolution Melting(HRM)is a post-PCR method developed to detect genetic variation in the nucleic acid sequence.Because of its simplicity,efficiency,accuracy and reliability,more and more forensic researchers pay attention to HRM.In this paper,the principles and advantages of HRM technology were summarized,and its application in non-human forensic biological evidence identification was reviewed.

关 键 词：法医学 高分辨率熔解曲线 非人源性物证 

分 类 号：D919.4[医药卫生—法医学]