MRI影像组学在轻度认知障碍中的研究进展  

Research progress of MRI radiomics in mild cognitive impairment

作　　者：蔡丽娜 李晓陵[2] 潘洋 王鹏 彭彩亮[2] 韩胜旺 侯玉 王杨 高瑞雪 CAI Lina;LI Xiaoling;PAN Yang;WANG Peng;PENG Cailiang;HAN Shengwang;HOU Yu;WANG Yang;GAO Ruixue(Graduate School of Heilongjiang University of Chinese Medicine,Harbin 150040,China;Department of CT&MR,the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China;Heilongjiang College of Traditional Chinese Medicine,Harbin 150036,China;Department of Rehabilitation,the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin 150001,China;Department of Gynecology,Harbin Hospital of Traditional Chinese Medicine,Harbin 150010,China)

机构地区：[1]黑龙江中医药大学研究生院,哈尔滨150040 [2]黑龙江中医药大学附属第一医院CT磁共振科,哈尔滨150040 [3]黑龙江省中医药科学院,哈尔滨150036 [4]黑龙江中医药大学附属第二医院康复科,哈尔滨150001 [5]哈尔滨市中医医院妇科,哈尔滨150010

出　　处：《磁共振成像》2022年第6期131-134,共4页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金面上项目(编号:82074537);黑龙江省自然科学基金项目(编号:LH2020H103);哈尔滨市科技创新人才优秀学科带头人基金(编号:2016RAXYJ096)。

摘　　要：轻度认知障碍(mild cognitive impairment,MCI)是阿尔茨海默病(Alzheimer’s disease,AD)的早期表现。目前尚无有效根治AD的方法。因此,MCI早期诊断和干预对预防或延缓AD的发展具有重要意义。MRI影像组学以非侵入性方式高通量提取和分析MCI患者影像图像特征,提供更多潜在的影像学生物标志物信息,进而指导临床进行精准诊疗,具有广阔的发展前景。本文就影像组学概念、MRI影像组学在MCI诊断、分类及进展预测中的相关研究加以综述。Mild cognitive impairment(MCI)is the early manifestation of Alzheimer’s disease(AD).At present,there is no effective radical cure for AD.Therefore,early diagnosis and intervention of MCI are of great significance to prevent or delay the development of AD.MRI radiomics can extract and analyze the features of MCI patients’images in a non-invasive way,which can provide more potential imaging biomarker information,and then guide clinical accurate diagnosis and treatment,which has a broad development prospect.This paper reviews the concept of radiomics and the research progress of MRI radiomics in the diagnosis,classification and conversion prediction of MCI.

关 键 词：磁共振成像 影像组学 轻度认知障碍 阿尔茨海默病 

分 类 号：R445.2[医药卫生—影像医学与核医学] R749.16[医药卫生—诊断学]