猴痘疫情现状及防控挑战  

Progression and challenges in prevention and control of monkeypox epidemic

作　　者：王文鑫 福军亮[1,2] 王福生 WANG Wen-xin;FU Jun-liang;WANG Fu-sheng(Senior Department of Infectious Diseases,Peking University 302 Clinical Medical School,100039,China;Senior Department of Infectious Diseases,Fifth Medical Center of Chinese PLA General Hospital,Beijing 100039,China)

机构地区：[1]北京大学三○二临床医学院感染病医学部,100039 [2]解放军总医院第五医学中心感染病医学部,北京100039

出　　处：《传染病信息》2022年第3期197-201,共5页Infectious Disease Information

基　　金：国家自然科学基金创新研究群体项目(81721002)。

摘　　要：猴痘是由猴痘病毒引起的人畜共患病,既往主要流行于非洲西部和中部。2022年5月以来,非洲以外地区的猴痘病例逐渐增多,患者多无流行地区旅行史,这次疫情引发全球关注。猴痘为自限性疾病,临床表现与天花相似,但程度较轻。PCR或核酸测序有助于确诊猴痘。猴痘目前尚无特效疗法,可通过接种天花疫苗预防。鉴于本轮疫情中猴痘病毒传播途径未知且基因出现“超突变”,不排除猴痘出现大流行的可能。各国需要高度警惕并采取必要的防控措施。Monkeypox is a zoonotic disease caused by the monkeypox virus, which was mainly prevalent in the west and central Africa in the past. Monkeypox cases outside Africa have increased in recent days, and most of them have no travel history to endemic areas, causing global concern. Monkeypox is a self-limited disease with clinical manifestations similar to smallpox but to a lesser degree.Monkeypox can be confirmed by polymerase chain reaction or nucleic acid sequencing. Monkeypox can not be cured with specific drugs but prevented with the smallpox vaccine. Given the monkeypox virus transmission chain unknown and the phenomenon of “super mutation” in its genesduring this outbreak, a monkeypox pandemic cannot be ruled out. Countries need to be on high alert and take necessary measures.

关 键 词：猴痘 猴痘病毒 非流行地区 现状 天花疫苗 超突变 大流行 疾病防控 新/突发传染病 

分 类 号：R725.1[医药卫生—儿科]