电子计算机断层扫描引导下经皮肺穿刺活检磨玻璃结节的诊断价值  

Diagnostic value of computed tomography guided percutaneous transthoracic needle biopsy(PTNB)for ground-glass nodule

作　　者：钱坤[1] 赵昕[1] 谭晓刚[1] 田笑如 刘幸生 张毅[1] Qian Kun;Zhao Xin;Tan Xiaogang;Tian Xiaoru;Liu Xingsheng;Zhang Yi(Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China)

机构地区：[1]首都医科大学宣武医院胸外科,北京100053

出　　处：《首都医科大学学报》2022年第4期558-563,共6页Journal of Capital Medical University

基　　金：首都医学发展科研基金(2022-2-2013)。

摘　　要：目的探讨电子计算机断层扫描(computed tomography,CT)引导下经皮肺穿刺活检磨玻璃结节(ground-glass nodule,GGN)的诊断价值。方法回顾性分析2014年1月至2019年1月期间217例接受CT引导下经皮肺穿刺活检的GGN患者的临床病理资料,对穿刺为恶性的病例判断为阳性,对于穿刺为良性的患者结合随访结果做出临床诊断,将穿刺病理与临床最终诊断作对比。根据临床特点进行分组,统计分析每组穿刺活检的准确率、灵敏度、阴性预测值及并发症发生率。结果217例患者总体准确率93.5%(203/217),灵敏度92.2%(165/179),阴性预测值为73.1%(38/52)。并发症总体发生率35.5%,以咯血和气胸为主。结论CT引导下对GGN穿刺活检具有较高的准确性和灵敏度,但需要警惕假阴性的结果,妥善处理并发症。Objective To investigate the diagnostic value of computed tomography(CT)guided percutaneous transthoracic needle biopsy(PTNB)for ground-glass nodule(GGN).Methods The clinicopathological data of 217 patients with GGN who underwent CT guided PTNB from January 2014 to January 2019 were retrospectively analyzed.The cases with malignant puncture were judged to be positive.The patients with benign puncture were clinically diagnosed in combination with the follow-up results,and the puncture pathology was compared with the final clinical diagnosis.The accuracy,sensitivity,negative predictive value,and complication rate of puncture biopsy in each group were statistically analyzed.Results The overall accuracy of 217 patients was 93.5%(203/217),the sensitivity was 92.2%(165/179),and the negative predictive value was 73.1%(38/52).The overall incidence of complications was 35.5%,mainly hemoptysis and pneumothorax.Conclusion CT guided PTNB GGN had high accuracy and sensitivity.It is necessary to be vigilant against false negative results and properly deal with complications.

关 键 词：磨玻璃结节 活检 诊断价值 

分 类 号：R655.3[医药卫生—外科学]