2018-2019年甘肃省大骨节病现症患者调查分析  

Investigation and analysis of patients with Kaschin-Beck disease in Gansu Province from 2018 to 2019

作　　者：陈晓燕[1] 陈发青 王燕玲[1] 窦瑜贵[1] 费秀兰 郑菁[1] 陈国华[1] 孙玮[1] 曹永琴[1] 罗小霞 Chen Xiaoyan;Chen Faqing;Wang Yanling;Dou Yugui;Fei Xiulan;Zheng Jing;Chen Guohua;Sun Wei;Cao Yongqin;Luo Xiaoxia(Department for Endemic Disease Control,Gansu Center for Disease Prevention and Control,Lanzhou 730000,China;School of Public Health,Gansu University of Traditional Chinese Medicine,Lanzhou 730000,China)

机构地区：[1]甘肃省疾病预防控制中心地方病防制科,兰州730000 [2]甘肃省中医药大学公共卫生学院,兰州730000

出　　处：《中华地方病学杂志》2022年第6期450-454,共5页Chinese Journal of Endemiology

基　　金：甘肃省中医药管理局科研课题(GZK-2019-57);兰州市人才创新创业项目(2021-RC-110)。

摘　　要：目的分析甘肃省大骨节病现症患者状况,为开展大骨节病患者精准救治提供科学依据。方法2018-2019年,在甘肃省大骨节病病区,以病区县(区)为单位开展大骨节病现症患者个案调查、临床检查及X线拍片检查。调查内容包括患者的基本信息、临床诊断分度、病情信息、手术及药物治疗情况等。结果共确诊大骨节病现症患者23909例,分布在7个市(州)的37个县(区),Ⅰ、Ⅱ、Ⅲ度患者分别占64.04%(15312例)、26.12%(6244例)、9.84%(2353例);患者以50岁以上(90.74%,21694例),汉族(97.15%,23228例),农民(99.25%,23729例)为主。患者以多个部位关节增粗变形(89.30%,21350例),疼痛(87.04%,20810例)为主,且关节增粗变形、疼痛均多见于指关节、膝关节、踝关节,3个关节增粗变形分别占89.97%(21512例)、78.18%(18692例)、63.81%(15257例),疼痛分别占80.66%(19285例)、78.75%(18828例)、64.50%(15422例);83.83%(20044例)的患者有关节休息痛,82.63%(19757例)的患者有关节运动痛,76.03%(18177例)的患者有关节晨僵。完成手术治疗的患者占1.97%(470例)。长期药物治疗(全年用药超过6个月)的患者占47.78%(11424例);每年药物治疗费用以500元以下为主,占57.72%(13800例)。结论甘肃省大骨节病现症患者生存质量较低,应提高对成人大骨节病患者的重视度并加强管理与救治力度。Objective To investigate and analyze the living conditions of patients with Kaschin-Beck disease in Gansu Province,and to provide scientific basis for accurate treatment of the patients.Methods From 2018 to 2019,case investigation,clinical examination and X-ray examination of patients with Kaschin-Beck disease were carried out in the Kaschin-Beck disease area of Gansu Province.The contents of the survey included basic information of the patients,clinical diagnosis classification,disease information,surgery and drug treatment,etc.Results A total of 23909 patients with Kaschin-Beck disease were diagnosed in 37 counties(districts)of 7 cities(states).The patients with gradeⅠ,gradeⅡand gradeⅢaccounted for 64.04%(15312 cases),26.12%(6244 cases)and 9.84%(2353 cases),respectively;90.74%(21694 cases)of the patients were over 50 years old,Han nationality was 97.15%(23228 cases),and peasants were 99.25%(23729 cases).The patients mainly had multiple joint thickening and deformation(89.30%,21350 cases)and pain(87.04%,20810 cases).Joint thickening and deformation and pain were more common in finger joint,knee joint and ankle joint.The thickening and deformation of the three joints accounted for 89.97%(21512 cases),78.18%(18692 cases)and 63.81%(15257 cases),respectively;pain accounted for 80.66%(19285 cases),78.75%(18828 cases)and 64.50%(15422 cases),respectively;83.83%(20044 cases)had joint rest pain,82.63%(19757 cases)had joint movement pain and 76.03%(18177 cases)had joint morning stiffness.Surgical treatment was completed in 1.97%(470 cases).Long-term drug treatment(more than 6 months in the whole year)accounted for 47.78%(11424 cases);the annual cost of drug treatment was mainly less than 500 yuan,accounting for 57.72%(13800 cases).Conclusions The quality of life of patients with Kaschin-Beck disease in Gansu Province is low.We should pay more attention to adult patients with Kaschin-beck disease and strengthen management and treatment.

关 键 词：大骨节病 调查 分析 

分 类 号：R684.1[医药卫生—骨科学]