成都市2010—2019年新报告HIV/AIDS病例晚发现的影响因素及晚发现病例的生存情况分析  

Analysis of factors influencing late detection of newly reported HIV/AIDS cases and survival of late detected cases in Chengdu from 2010 to 2019

作　　者：施雅莹[1] 余继熙 刘芳[1] 何勤英[1] 吴学庆[1] 朱彦锋 SHI Ya-ying;YU Ji-xi;LIU Fang;HE Qin-ying;WU Xue-qing;ZHU Yan-feng(Department of STD/AIDS Prevention and Control,Chengdu Center for Disease Control and Prevention,Chengdu,Sichuan 610041,China;不详)

机构地区：[1]成都市疾病预防控制中心性病艾滋病防制科,四川成都610041 [2]成都医学院公共卫生学院,四川成都610500

出　　处：《现代预防医学》2022年第12期2143-2148,共6页Modern Preventive Medicine

基　　金：老龄化背景下成都老年男性HIV/AIDS人群艾滋病易感机制研究(YLZBS2002);基于保护动机理论的青年学生艾滋病健康教育模式构建及实践(SXJYB2109)。

摘　　要：目的了解成都市艾滋病病毒感染者和艾滋病病人(简称HIV/AIDS)的晚发现情况及主要影响因素,为当地艾滋病防控工作提供建议。方法收集成都市2010—2019年10年间新报告的HIV/AIDS的数据,采用χ;检验和多因素logistic回归分析,计算比值比,95%可信区间值。分析不同病例生存情况并绘制生存曲线。结果共纳入39230例研究对象,总晚发现率为34.4%,多因素logistic回归分析显示,女性出现晚发现的可能性更低(OR=0.77,95%CI:0.73~0.82),随年龄增加出现晚发现的可能性逐渐增高,家务、家政及待业较农民更易出现晚发现(OR=1.12,95%CI:1.05~1.19),外地户籍较本地户籍出现晚发现可能性更低(OR=0.83,95%CI:0.79~0.88),以医院就诊人群为参考,样本来源为重点人群(OR=0.65,95%CI:0.61~0.68)、羁押人群(OR=0.25,95%CI:0.20~0.31)、献血人群(OR=0.31,95%CI:0.25~0.39)和其他(OR=0.50,95%CI:0.42~0.59)出现晚发现的可能性更低。晚发现病例生存时间为(32.3±30.8)月,非晚发现病例为(42.1±31.6)月。结论成都市近几年发现的HIV/AIDS晚发率呈下降趋势。性别、年龄、样本来源是晚发现的影响因素,非晚发现病例的平均生存时间远高于晚发现病例的平均生存时间。Objective To understand the late detection of HIV-infected and AIDS patients(referred to as HIV/AIDS)in Chengdu and the main influencing factors,and to provide suggestions for local AIDS prevention and control.Methods Data on newly reported HIV/AIDS in Chengdu city during the 10-year period from 2010 to 2019 were collected,and the odds ratio(OR),95%confidence interval(CI)values were calculated using Chi-square test and multi-factor logistic regression analysis.Survival of different cases was analyzed and survival curves were plotted.Results A total of 39230 study subjects were included,with an overall late detection rate of 34.4%.Multifactorial logistic regression analysis showed that women were less likely to have late detection(OR=0.77,95%CI:0.73-0.82),with a progressively higher likelihood of late detection with increasing age,people doing housework,domestic work,and waiting for work opportunity were more likely to have late detection than farmers(OR=1.12,95%CI:1.05-1.19),and migrant people from other provinces were less likely to have late detection than locally registered residents(OR=0.83,95%CI:0.79-0.88).Using the hospital visit population as a reference,and the sample source of key population(OR=0.65,95%CI:0.61-0.68),custodial population(OR=0.25,95%CI:0.20-0.31),blood donor population(OR=0.31,95%CI:0.25-0.39)and others(OR=0.50,95%CI:0.42-0.59)were less likely to have late detection.The survival time was(32.3±30.8)months for late detection cases and(42.1±31.6)months for non-late detection cases.Conclusion The late detection rate of HIV/AIDS in Chengdu has shown a decreasing trend in recent years.Gender,age,and sample source are influencing factors of late detection,and the mean survival time of non-late-detected cases is much higher than the mean survival time of late-detected cases.

关 键 词：HIV/AIDS 晚发现 影响因素 生存时间 

分 类 号：R512.91[医药卫生—内科学] R181.3[医药卫生—临床医学]