良性前列腺增生患者术后发生远期血尿的危险因素分析  

Risk factors for postoperative long-term hematuria in patients with benign prostatic hyperplasia

作　　者：罗卫平[1] 赵友 黄鑫 聂军[1] LUO Wei-ping;ZHAO You;HUANG Xin;NIE Jun(Department of Urology,Liyang People's Hospital,Liyang,Jiangsu 213300,China)

机构地区：[1]溧阳市人民医院泌尿外科,江苏溧阳213300

出　　处：《中华男科学杂志》2022年第5期422-426,共5页National Journal of Andrology

摘　　要：目的:探讨良性前列腺增生患者术后发生远期血尿的危险因素。方法:回顾性分析2015年1月至2020年1月于溧阳市人民医院泌尿外科住院行经尿道手术治疗的646例良性前列腺增生患者的资料,根据术后远期随访时是否发生血尿分为血尿组和无血尿组,比较两组患者的临床资料,记录可能与术后远期发生血尿的相关因素,通过单因素和多因素分析找出术后发生远期血尿的独立危险因素。结果:646例患者中,发生血尿48例,未发生血尿598例。单因素分析显示合并高血压、糖尿病、腺体残留、泌尿道感染、膀胱颈挛缩、前列腺癌、尿道结石、尿道狭窄、过度活动、便秘是良性前列腺增生术后远期血尿的影响因素(P<0.05)。多因素分析显示合并高血压(P<0.001)、糖尿病(P=0.007)、腺体残留(P=0.013)、泌尿道感染(P<0.001)、膀胱颈挛缩(P=0.032)、尿道结石(P=0.033)、尿道狭窄(P=0.001)是良性前列腺增生术后发生远期血尿的独立危险因素。结论:患者合并高血压、糖尿病、腺体残留、泌尿道感染、膀胱颈挛缩、尿道结石、尿道狭窄是良性前列腺增生术后发生远期血尿的独立危险因素。Objective:To explore the risk factors for long-term hematuria after operation in BPH patients.Methods:We retrospectively analyzed the clinical data on 646 cases of BPH treated by transurethral surgery in Liyang People’s Hospital from January 2015 to August 2020.According to the incidence of hematuria at 3 months or longer after surgery,we divided the patients into a hematuria and a non-hematuria group,recorded the related factors,and investigated the independent risk factors for long-term hematuria by univariate and multivariate analyses.Results:Of the 646 BPH patients,48 were found with and 598 without hematuria after transurethral surgery.Univariate analysis showed that hypertension,diabetes mellitus,residual prostate gland,urinary tract infection,bladder neck contracture,prostate cancer,urethral calculus,urethral stricture,excessive activity and constipation were the influencing factors(P<0.05),while multivariate logistic regression analysis revealed that hypertension(P<0.001),diabetes mellitus(P=0.007),residual prostate gland(P=0.013),urinary tract infection(P<0.001),bladder neck contracture(P=0.032),urethral calculus(P=0.033)and urethral stricture(P=0.001)were independent risk factors for long-term hematuria in the BPH patients after surgery.Conclusion:Complicated hypertension,diabetes mellitus,residual prostate gland,urinary tract infection,bladder neck contracture,urethral calculus and urethral stricture are independent risk factors for long-term hematuria in BPH patients after transurethral surgery.

关 键 词：良性前列腺增生 血尿 危险因素 

分 类 号：R697.3[医药卫生—泌尿科学] R696.8[医药卫生—外科学]