评价磁共振功能成像在乳腺癌新辅助化疗早期疗效评价中的应用价值  

The Value of Functional MRI in the Evaluation of Early Therapeutic Effect of Neoadjuvant Chemotherapy for Breast Cancer

作　　者：孙晓琳[1] SUN Xiao-lin(Department of Radiology,Affiliated Central Hospital of Shenyang Medical College,Liaoning Shenyang 110000)

机构地区：[1]沈阳医学院附属中心医院放射科,辽宁沈阳110000

出　　处：《中国医疗器械信息》2022年第12期100-102,共3页China Medical Device Information

摘　　要：目的:探讨磁共振功能成像在乳腺癌新辅助化疗早期疗效,评价其应用价值。方法:选择2018年7月~2019年9月在本院进行诊治的乳腺癌患者,随机抽取数量为82例,根据双盲分组法将研究对象分为两组,将肿瘤最大直径<4.5cm的患者分为研究组,将肿瘤最大直径≥4.5cm者分为参照组,对比两组患者NAC前与后5个周期内的磁共振功能显示情况。结果:研究组新辅助化疗后NAC前肿瘤最大直径从原本的(4.59±1.90)cm缩短到(3.00±2.21)cm(P<0.05);观察组NAC前AD值从原本的(0.90±0.22)×10^(-3)mm^(2)/s增加到(1.01±0.30)10^(-3)mm^(2)/s(P<0.05)。结论:乳腺癌新辅助化疗早期评价中,选择磁共振功能成像技术能够有效的进行效果评估,实施安全性、可靠性较高。Objective:To explore the early effect of MRI in neoadjuvant chemotherapy of breast cancer and evaluate its application value.Methods:The breast cancer patients who were diagnosed and treated in our hospital from July 2018 to September 2019 were selected,and the number of randomly selected 82 cases was divided into two groups according to the double-blind grouping method.The patients were divided into the study group,and those with the largest tumor diameter≥4.5 cm were divided into the reference group,and the magnetic resonance function display of the two groups before and after NAC within 5 cycles was compared.Results:After neoadjuvant chemotherapy,the maximum diameter of pre NAC tumor in the study group was shortened from the original(4.59±1.90)cm to(3.00±2.21)cm(P<0.05);The AD value in the observation group increased from the original(0.90±0.22)×10^(-3)mm^(2)/s to(1.01±0.30)10^(-3)mm^(2)/s(P<0.05).Conclusion:In the early evaluation of neoadjuvant chemotherapy for breast cancer,MR functional imaging technology can effectively evaluate the effect,with high safety and reliability.

关 键 词：磁共振功能成像 乳腺癌 新辅助化疗 早期疗效 

分 类 号：R445.2[医药卫生—影像医学与核医学]