急性一氧化碳中毒患者首次进行高压氧治疗的时机及其对神经功能恢复和生活质量的影响  

Time of First Hyperbaric Oxygen Treatment in Patients with Acute Carbon Monoxide Poisoning and Its Impact on Nerve Function Recovery and Quality of Life

作　　者：陈丹娜[1] 卢晓航[1] 林岱敏[1] 林洪珊[1] 陈秋华 陈晓洁[1] CHEN Dan-na;LU Xiao-hang;LIN Dai-min;LIN Hong-shan;CHEN Qiu-hua;CHEN Xiao-jie(Hyperbaric Oxygen Department,Jieyang People’s Hospital,Guangdong Jieyang 522000)

机构地区：[1]揭阳市人民医院高压氧科,广东揭阳522000

出　　处：《中国医疗器械信息》2022年第12期142-144,共3页China Medical Device Information

摘　　要：目的:探讨首次进行高压氧治疗时机对急性一氧化碳中毒患者神经功能恢复和生活质量的影响。方法:选取2019年4月~2021年4月在本院进行治疗的360例急性一氧化碳中毒患者为研究对象,所选患者均进行高压氧治疗。根据高压氧治疗时机将患者分为超早期组(中毒6h内治疗210例)、早期组(中毒后6~12h内治疗110例)及普通组(12~24h内治疗40例),对治疗效果进行分析。结果:在治疗前,患者的对比指标数据评分无较大差异(P>0.05)。在治疗后,超早期组格拉斯哥昏迷指数评分、认知功能评分较早期组、普通组高,超早期组患者的迟发性脑病发生率、C反应蛋白指标较早期组、普通组低,昏迷时间更短,数据对比有统计学意义(P<0.05)。结论:超早期对急性一氧化碳中毒患者开展高压氧治疗的效果比较明显,能够加快中毒的消除速度,对患者的生活质量和神经功能的恢复起到更好的作用,预后得到改善。Objective:To investigate the effect of the first hyperbaric oxygen treatment on neurological recovery and quality of life in patients with acute carbon monoxide poisoning.Methods:360 patients with acute carbon monoxide poisoning from April 2019 to April 2021 were selected,and all the selected patients were treated with hyperbaric oxygen.According to the timing of hyperbaric oxygen treatment,patients were divided into super early groups(210 treated within 6 hours),early group(110 treated within 6-12 hours after poisoning)and general group(40 treated within 12-24 hours).Results:There was no significant difference in the comparison index data scores before treatment(P>0.05).After treatment,the Glasgow coma index score and intellectual status score were higher in the super early group,and in the early and general group,the incidence of late onset encephalopathy,C response protein index were lower than in the early and general group,and the data comparison had statistical significance(P<0.05).Conclusion:Hyperbaric oxygen treatment in patients with acute carbon monoxide poisoning,which can accelerate the elimination of poisoning,play a better effect on the quality of life and nerve function,and improve the prognosis.

关 键 词：急性一氧化碳中毒 高压氧 神经功能 生活质量 时间 智力状态 

分 类 号：R181.32[医药卫生—流行病学]