纯次氯酸喷涂治疗PICC穿刺点感染的效果研究  

The study on the effect of pure hypochlorite spray in the treatment of PICC puncture point infection

作　　者：钟玲玲[1] ZHONG Lingling(Department of International Medical Center,Zhejiang Provincial Tongde Hospital,Hanghzou 310012,China)

机构地区：[1]浙江省立同德医院国际医疗中心,浙江杭州310012

出　　处：《中国现代医生》2022年第18期123-125,140,共4页China Modern Doctor

基　　金：浙江省医药卫生科技计划项目(2019KY349)。

摘　　要：目的探讨纯次氯酸喷涂治疗外周中心静脉置管(PICC)穿刺点感染的治疗效果。方法选取2019年4月~2020年10月浙江省立同德医院收治的64例PICC穿刺点感染患者纳入本次研究,按照随机数字表法分为试验组和对照组,每组各32例。对照组采用碘伏湿敷进行治疗,试验组采用纯次氯酸喷涂治疗。对比两组患者的换药次数、治愈时间及治疗费用、感染治疗效果,比较两组患者局部皮肤的并发症发生情况。结果试验组的换药次数、治愈时间和治疗费用均明显低于对照组(P<0.001);试验组的总有效率为93.76%,明显高于对照组的75.00%(P<0.05);试验组患者在第1、2、3、4次换药时的细菌转阴率分别为28.13%、46.88%、81.25%和96.88%,均明显高于同期对照组(分别为6.25%、21.88%、56.25%和81.25%),差异有统计学意义(均P<0.05)。试验组局部皮肤的并发症总发生率为3.13%,明显低于对照组的18.76%,差异有统计学意义(P<0.05)。结论与碘伏湿敷相比,纯次氯酸喷涂在治疗PICC穿刺点感染上具有更好的临床治疗效果,治愈速度更快,治疗费用更低,治疗过程安全可靠,值得在临床上积极推广。Objective To explore the therapeutic effect of pure hypochlorite spray on the infection of puncture point of peripheral central vein catheter(PICC).Methods From April 2019 to October 2020,a total of 64 patients with PICC puncture point infection in our hospital were included in this study.They were divided into experimental group and control group by the random number table method,32 cases in each group.The control group was treated with iodophor wet compress,the experimental group was treated with pure hypochlorite spray.The frequency of dressing change,cure time and treatment cost of the two groups were compared,and the effect of infection treatment of the two groups was compared,the local skin complications of the two groups were recorded and compared.Results The number of drug changes,cure time and treatment cost of the patients in the experimental group were significantly lower than those of the control group(P<0.001).The total effective rate of the experimental group was 93.76%,which was significantly higher than that of the control group(75.00%)(P<0.05).The bacterial negative conversion rates of the experimental group at the first dressing change,the second dressing change,the third dressing change and the fourth dressing change were 28.13%,46.88%,81.25%and 96.88%,respectively,which were significantly higher than those of the control group at the same period(6.25%,21.88%,56.25%and 81.25%,respectively),and the differences between groups were statistically significant(all P<0.05).The total incidence of local skin complications in the experimental group was 3.13%,which was significantly lower than that of the control group(18.76%),the difference was statistically significant(P<0.05).Conclusion Compare with iodophor wet compress,pure hypochlorite spray in the treatment of PICC puncture point infection has better clinical treatment effect,faster cure speed,lower treatment cost,safe and reliable treatment process,which is worthy of active promotion in clinical practice.

关 键 词：外周中心静脉置管 纯次氯酸 穿刺点感染 局部皮肤并发症 

分 类 号：R644[医药卫生—外科学]