真空辅助旋切治疗乳腺良性叶状肿瘤的疗效及局部复发的相关因素分析  

Efficacy of Vacuum-Assisted Excision on Benign Phyllodes Tumors of Breast and Analysis of Related Factors of Local Recurrence

作　　者：姚岚雅 Yao Lanya(Xuchang Central Hospital,Xuchang 461000)

机构地区：[1]许昌市中心医院,河南许昌461000

出　　处：《哈尔滨医药》2022年第3期12-14,共3页Harbin Medical Journal

摘　　要：目的探究真空辅助旋切(VAE)治疗乳腺良性叶状肿瘤(PTB)的疗效及局部复发的相关因素。方法回顾性分析116例乳腺良性叶状肿瘤患者的临床资料,根据患者手术方式进行分组,进行真空辅助旋切治疗的患者为观察组(n=74),进行常规局部切除手术的患者为对照组(n=42)。比较两组患者手术指标(手术时间、切口长度、术中出血量)、术后并发症情况差异。两组患者均随访,根据患者是否局部复发进行分组,分为复发组(n=12)与未复发组(n=104),对患者资料进行单因素分析,对单因素分析存在统计学差异的指标进行多元Logistic回归分析。结果观察组患者手术时间、切口长度、术中出血量均低于对照组(P<0.05);观察组患者局部皮下瘀斑发生率低于对照组(P<0.05),两组患者局部血肿、切口感染、复发发生率差异无统计学意义(P>0.05)。单因素分析结果显示,复发组患者肿瘤大小、纤维腺瘤病史、手术切缘与未复发组患者差异显著(P<0.05),两组患者年龄、月经状态、手术方法差异无统计学意义(P>0.05);多因素logistic分析结果显示,肿瘤大小≥2.5cm(OR=1.571,P<0.001)、存在纤维腺瘤病史(OR=1.740,P<0.05)、手术切缘阳性(OR=1.394,P<0.05)是良性PTB患者复发的危险因素。结论VAE治疗良性PTB患者的疗效优于常规局部切除手术,肿瘤大小、纤维腺瘤病史及手术切缘是影响局部复发的相关因素。Objective To explore the efficacy of vacuum-assisted excision(VAE)in the treatment of benign phyllodes tumors of breast(PTB)and related factors of local recurrence.Methods The clinical data of 116 patients with benign phyllodes tumors of breast were retrospectively analyzed,and the patients were grouped according to the surgical methods.The patients who underwent vacuum-assisted excision were selected as observation group(n=74),and the patients undergoing routine local resection were set as control group(n=42).The differences in surgical indicators(surgical time,incision length,intraoperative blood loss)and postoperative complications were compared between the two groups.The two groups of patients were followed up and the patients were divided into recurrence group(n=12)and non-recurrence group(n=104)according to whether the patients had local recurrence.Univariate analysis was performed on the data of patients.Multivariate Logistic regression analysis was performed on indexes with significant differences in univariate analysis.Results The surgical time,incision length and intraoperative blood loss in observation group were lower than those in control group(all P<0.05).The incidence rate of local subcutaneous ecchymosis in observation group was lower than that in control group(P<0.05),and there were no significant differences in the incidence rates of local hematoma,incision infection and recurrence between the two groups(all P>0.05).Results of univariate analysis showed that the tumor size,a history of fibroadenoma and surgical margin in recurrence group were significantly different from those in non-recurrence group(all P<0.05),and there were no significant differences in the age,menstrual status and surgical methods between the two groups(all P>0.05).Multivariate Logistic analysis showed that tumor size≥2.5 cm(OR=1.571,P<0.001),a history of fibroadenoma(OR=1.740,P<0.05)and positive surgical margin(OR=1.394,P<0.05)were risk factors for recurrence in patients with benign PTB.Conclusion VAE has better efficacy

关 键 词：真空辅助旋切 乳腺良性叶状肿瘤 疗效 局部复发 相关性 

分 类 号：R457.2[医药卫生—治疗学]