The pathology,phylogeny,and epidemiology of Echinococcus ortleppi(G5 genotype):a new case report of echinococcosis in China  

作　　者：Xu Wang Aiya Zhu Hongying Cai Baixue Liu Gang Xie Rui Jiang Ji Zhang Nanzi Xie Yayi Guan Robert Bergquist Zhenghuan Wang Yang Li Weiping Wu 

机构地区：[1]National Institute of Parasitic Diseases,Chinese Center for Diseases Control and Prevention(Chinese Center for Tropical Diseases Research),NHC Key Laboratory of Parasite and Vector Biology,WHO Collaborating Centre for Tropical Diseases,National Center for International Research on Tropical Diseases,Shanghai,China [2]Guizhou Center for Disease Control and Prevention,Guiyang,Guizhou,China [3]不详

出　　处：《Infectious Diseases of Poverty》2021年第6期108-108,共1页贫困所致传染病（英文）

摘　　要：Background:Cystic echinococcosis(CE),caused by the larval stage of the complex Echinococcus granulosus sensu lato(s.l.),is a zoonotic parasitic disease with a high social burden in China.E.ortleppi is a species(formerly genotype 5 of E.granulosus s.l.)with unique epidemic areas(tropical areas),transmission patterns(mainly cattle origin),and pathological characteristics(large and small hook lengths)compared to other species that cause CE.A 19-year-old female patient in an area with no history of echinococcosis in Guizhou Province,China,was diagnosed with E.ortleppi infection in 2019.This study is to understand the source of this human E.ortleppi infection.Methods:We performed computer tomography(CT)scans,surgical operation,morphological sectioning,molecular diagnosis,phylogenetic analyses,and epidemiological investigation in Anshun City,Guizhou Province,China in 2019.Results:The patient presented with intermittent distension and pain in the upper abdomen without other abnormal symptoms.Routine blood examination results were normal.However,abdominal CT revealed a fertile cyst with a diameter of approximately 8 cm,uniform density,and a clear boundary,but without an evident cyst wall in the right lobe of the liver.The cyst was fertile,and phylogenetic analyses revealed that the isolates represented a new E.ortleppi genus haplotype.A result of 10‒14 years incubation period with indigenous infection was considered available for the case through the epidemiological survey.Conclusions:CE due to E.ortleppi infection can be confused with other diseases causing liver cysts,resulting in misdiagnosis.A transmission chain of E.ortleppi may exist or existed in the past in the previously considered nonendemic areas of echinococcosis in southwestern China.

关 键 词：Cystic echinococcosis(CE) Echinococcus ortleppi Human Non-endemic area China 

分 类 号：R532.32[医药卫生—内科学]