高压氧舱内同步脑仿生电刺激治疗突发性耳聋的疗效及血液流变学变化  

Curative effect of synchronous brain bionic electrical stimulation in hyperbaric oxygen chamber on patients with sudden deafness and the hemorheological indictors’changes

作　　者：董铭杰 薛瑞君 王平[1] 杨郑 徐紫晴 刘楠[1] 潘树义 郭大志 Dong Mingjie;Xue Ruijun;Wang Ping;Yang Zheng;Xu Ziqing;Liu Nan;Pan Shuyi;Guo Dazhi(Department of Hyperbaric Oxygen,The Sixth Medical Center,PLA General Hospital,Beijing 100048,China)

机构地区：[1]解放军总医院第六医学中心高压氧科,北京100048

出　　处：《中华航海医学与高气压医学杂志》2022年第1期61-64,共4页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

基　　金：北京市科技新星计划(Z161100004916144);首都市民健康项目培育(Z141100002114039);首都卫生发展科研专项(首发2018-4-5111)。

摘　　要：目的探讨高压氧舱内同步脑仿生电刺激治疗突发性耳聋(SD)的疗效及血液流变学变化。方法选取2020年6月至2021年6月解放军总医院第六医学中心高压氧科收治的SD门诊和住院患者128例,按照治疗方法分为2组,采用高压氧舱内同步脑电仿生电刺激仪治疗70例(研究组),采用常规高压氧治疗58例(对照组)。评价2组治疗效果;采用全自动生化分析仪比较2组患者治疗前后全血(高、低切)黏度、血浆黏度和红细胞聚集指数等血液流变学的变化。结果治疗2个疗程后,研究组治疗有效率(88.57%)明显高于对照组(79.31%),差异有统计学意义(P<0.05)。治疗后2组患者全血(高、低切)黏度、血浆黏度和红细胞聚集指数较治疗前均明显降低(P<0.05),且研究组明显低于对照组(P<0.05)。结论高压氧舱内同步脑仿生电刺激治疗可改善SD患者的血液流变学指标,减轻血液高凝状态,提高SD患者的听力水平和治疗效果,值得临床推广应用。Objective To explore the curative effect of synchronous bionic electrical stimulation in hyperbaric oxygen chamber on patients with sudden deafness(SD)and the changes in hemorheological indicators.Methods A total of 128 SD outpatients and inpatients treated at the Hyperbaric Oxygen Department of the Sixth Medical Center of the Chinese PLA General Hospital from June 2020 to June 2021 were randomly divided into study group(70 cases treated with synchronous brain bionic electrical stimulator in hyperbaric oxygen chamber)and control group(58 cases given conventional hyperbaric oxygen therapy),respectively.The curative effects of the two groups were evaluated,and the hemorheological indicators,such as the whole blood(high-shear and low-shear)viscosity,plasma viscosity,and red blood cell aggregation,were analyzed by the automatic biochemical analyzer before and after treatment.Results After two courses of treatments,the overall effective rate of the study group(88.57%)was significantly higher than that of the control group(79.31%),and the difference was statistically significant(P<0.05).After treatment,the whole blood(high-shear and low-shear)viscosities,plasma viscosity,and erythrocyte aggregation indicators of the two groups were significantly decreased compared with those before treatment(P<0.05),and the above indicators in the study group were significantly lower than those in the control group(P<0.05).Conclusions Synchronous brain bionic electrical stimulation in the hyperbaric oxygen chamber can improve the hemorheological indicators of the SD patients,reduce their blood hypercoagulability,and improve their hearing level and treatment effect.Hence,it is worth of clinical promotion.

关 键 词：高压氧 同步脑仿生电刺激 突发性耳聋 血液流变学 

分 类 号：R764.437[医药卫生—耳鼻咽喉科]