Ten-year experience with penile prosthetic surgery for the treatment of erectile dysfunction:outcomes of a tertiary referral center and predictors of early prosthetic infection  

作　　者：Franco Palmisano Luca Boeri Riccardo Ievoli Josvany Sánchez-Curbelo Matteo Giulio Spinelli Andrea Gregori Antonio Maria Granata Eduard Ruiz-Castane Emanuele Montanari Joaquim Sarquella-Geli 

机构地区：[1]ASST Fatebenefratelli-Sacco,Department of Urology,Luigi Sacco University Hospital,Milan 20157,Italy [2]IRCCS Foundation Ca’Granda Ospedale Maggiore Policlinico,Department of Urology,University of Milan,Milan 20122,Italy [3]Department of Economics and Management,University of Ferrara,Ferrara 44121,Italy [4]FundacióPuigvert,Department of Andrology,University of Barcelona,Barcelona 08025,Spain

出　　处：《Asian Journal of Andrology》2022年第1期32-39,共8页亚洲男性学杂志（英文版）

摘　　要：We aimed to evaluate ten-year outcomes of penile prosthesis(PP)implantation for the treatment of erectile dysfunction and to assess predictors of early prosthetic infection(EPI).We identified 549 men who underwent 576 PP placements between 2008 and 2018.Univariate and multivariate analyses were used to identify potential predictors of EPI.An EPI predictive nomogram was developed.Thirty-five(6.1%)cases of EPI were recorded with an explant rate of 3.1%.In terms of satisfaction,82.0%of the patients defined themselves as“satisfied,”while partner’s satisfaction was 88.3%.Diabetes(P=0.012),longer operative time(P=0.032),and reinterventions(P=0.048)were associated with EPI risk,while postoperative ciprofloxacin was inversely associated with EPI(P=0.014).Rifampin/gentamicin-coated 3-piece inflatable PP(r/g-c 3IPP)showed a higher EPI risk(P=0.019).Multivariate analyses showed a two-fold higher risk of EPI in diabetic patients,redo surgeries,or when a r/g-c 3IPP was used(all P<0.03).We showed that diabetes,longer operative time,and secondary surgeries were the risk factors for EPI.Postoperative ciprofloxacin was associated with a reduced risk of EPI,while r/g-c 3IPP had higher EPI rates without an increased risk of PP explant.After further validation,the proposed nomogram could be a useful tool for the preoperative counseling of PP implantation.

关 键 词：BOSTON Coloplast Titan three-piece penile prosthesis erectile dysfunction IMPOTENCE Inhibizone patient satisfaction penile prosthesis prosthesis infection rifampin soaking 

分 类 号：R697.1[医药卫生—泌尿科学]