广州增江沿岸地区鼠形动物及携带病原体调查  

Investigation of pathogens in mouse-like animals in Zeng River area,Guangzhou

作　　者：吴涛宇 逄博[2] 冯海燕 王显军 李浩[1] 陈守义 张齐光[3] 丁淑军 马伟[1] 杨丽萍 WU Tao-yu;PANG Bo;FENG Hai-yan;WANG Xian-jun;LI Hao;CHEN Shou-yi;ZHANG Qi-guang;DING Shu-jun;MA Wei;YANG Li-ping(Department of Epidemiology,School of Public Health,Cheeloo College of Medicine,Shandong University,Ji’nan 250012,China;Shandong Center for Disease Control and Prevention,Ji’nan 250014,China;Zengcheng District Center for Disease Control and Prevention,Guangzhou 511300,China;Guangzhou Center for Disease Control and Prevention,Guangzhou 510440,China)

机构地区：[1]山东大学齐鲁医学院公共卫生学院流行病学系,济南250012 [2]山东省疾病预防控制中心,济南250014 [3]广州市增城区疾病预防控制中心,广州511300 [4]广州市疾病预防控制中心,广州510440

出　　处：《中国人兽共患病学报》2022年第6期486-489,495,共5页Chinese Journal of Zoonoses

摘　　要：目的了解广州增江沿岸地区鼠形动物及携带伯氏疏螺旋体、钩端螺旋体、恙虫病东方体、埃立克体、新型布尼亚病毒和汉坦病毒6种病原体的情况。方法使用笼夜法在广州市增城区捕获鼠形动物,利用荧光定量PCR方法检测鼠形动物脏器中的伯氏疏螺旋体、钩端螺旋体、恙虫病东方体、埃立克体、新型布尼亚病毒和汉坦病毒。采用χ2检验和Fisher确切概率法比较不同种属、雌雄和调查点鼠形动物病原体的感染情况。结果捕获臭鼩鼱和褐家鼠共69只,鼠形动物密度为13.29%。褐家鼠中检出钩端螺旋体为57.89%、恙虫病东方体为31.58%、汉坦病毒为21.05%和伯氏疏螺旋体为5.26%;臭鼩鼱中仅检出伯氏疏螺旋体为2.00%。埃立克体、新型布尼亚病毒均未检出。此外,褐家鼠中存在4种病原体的双重感染,其双重感染率为36.84%。结论广州增江沿岸地区鼠形动物以臭鼩鼱和褐家鼠为主且密度较高;褐家鼠中病原体感染率高于臭鼩鼱且存在多种病原体的复合感染。当地应加强对鼠形动物尤其是褐家鼠的监测和控制、降低鼠形动物密度。To investigate the mouse-like animals and the carriers of Borrelia burgdorferi,Leptospira,Orientiatsutsugamushi,Ehrlichia,severe thrombocytopenia with fever syndrome virus(SFTSV),and hantavirus in the area along the Zeng River,Guangzhou,mouse-like animals were captured using the cage-trap method from Zengcheng District,during November 2020.Species were identified and DNA/RNA samples were extracted from viscera.Quantitative polymerase chain reaction(qPCR)was used to detect the six pathogens.To analyze the infection of mouse-like animals of different species,sex and surveillance points,we used the Chi-square test and Fisher test in R 4.0.3software.A total of 69mouse-like animals were captured,with a rodent density of 13.29%in the Zeng River area,Guangzhou.Borrelia burgdorferi,Leptospira,Orientiatsutsugamushi,and hantavirus were detected in Rattusnorvegicus,with infection rates of 57.89%,31.58%,21.05%and 5.26%.Suncus murinus carried only Borrelia burgdorferi;Ehrlichia and SFTSV were not detected.Co-infection with the four pathogens was found in R.norvegicus,with a co-infection rate of 36.84%.The principal species of mouse-like animals with high density along Zengjiang River area,Guangzhou were S.murinus and R.norvegicus.The infection rate of pathogens in R.norvegicus was higher than that in S.murinus,and there were various types of co-infection in R.norvegicus.Surveillance should be enhanced in mouse-like animals,particularly R.norvegicus,and measures taken to reduce rodent density.

关 键 词：鼠形动物 病原体 双重感染 广州 增江沿岸 

分 类 号：R183.5[医药卫生—流行病学] R377.5[医药卫生—公共卫生与预防医学]