基于咪唑并[1,2-α]吡啶结构turn-on型碱土金属离子传感器的合成与性质研究  

Synthesis and properties of a turn-on alkaline-earth metal ion sensor based on imidazo[1,2-α]pyridine structure

作　　者：张细稳 ZHANG Xiwen(Jiangxi Science and Technology Normal University,Jiangxi Provincial Key Laboratory of Organic Chemistry,Nanchang 330013,China)

机构地区：[1]江西科技师范大学,有机功能分子研究所,南昌330013

出　　处：《江西化工》2022年第3期102-106,共5页Jiangxi Chemical Industry

基　　金：江西省教育厅青年基金(GJJ190614);江西省科技厅青年科学基金(20202BAB213006)的资助。

摘　　要：本文通过多组分反应高效的合成了咪唑并[1,2-α]吡啶衍生物1,并详细研究了其对金属离子的荧光响应。化合物1在吡啶的N的邻位存在两个咪唑并[1,2-α]吡啶骨架结构,构成了N,N,N三齿的结合位点,它与碱土金属离子Mg^(2+)、Ca^(2+)、Sr^(2+)作用后有明显的荧光增强,发射出明亮的绿色荧光,并且对其他金属离子的响应及其微弱。化合物1对Mg^(2+)、Ca^(2+)、Sr^(2+)三种离子的检测限分别为21 nM、48 nM和43 nM,为检测碱土金属离子提供了可能。In this paper,imidazo[1,2-α]pyridine derivative 1 was synthesized efficiently through multi-component reaction,meanwhile its fluorescence response to metal ions was studied thoroghly.There are two imidazo[1,2-α]pyridine structural units beside the N of pyridine of Compound 1,forming a N,N,N tridentate ligand.After interacting with alkaline-earth metal ions Mg^(2+),Ca^(2+),Sr^(2+),it has obvious fluorescence enhancement,emitting bright green fluorescence,and extremely weak response to other metal ions.The detection limits of Compound 1 for Mg^(2+),Ca^(2+)and Sr^(2+)ions were 21 nM,48 nM and 43 nM,respectively,which provided a possibility for the detection of alkaline earth-metal ions.

关 键 词：咪唑并[1 2-α]吡啶 碱土金属离子 荧光传感器 

分 类 号：O657.3[理学—分析化学] TP212[理学—化学]