心肝肾三脏同治方对更年期女性失眠的队列研究  

Cohort study of Heart,Liver and Kidney Tongzhi Prescription for Insomnia in Menopausal Women

作　　者：白旭晶[1] 马毅[1] BAI Xujing;MA Yi(Beijing Geriatric Hospital,Beijing 100095,China)

机构地区：[1]北京老年医院,北京100095

出　　处：《云南中医学院学报》2021年第6期41-44,共4页Journal of Yunnan University of Traditional Chinese Medicine

基　　金：2018年度首都卫生发展科研专项(首发2018-1-2191)。

摘　　要：目的更年期失眠的女性大多有心、肝、肾三脏同时受累的表现,通过临床观察明确三脏同治方的临床疗效。方法通过对210例更年期失眠妇女,分别观察不同组别的治疗效果和更年期伴随症状的改善情况,进行统计学差异性比较。结果通过临床对比发现,在睡眠改善的总有效率方面,与对照组比较,具有统计学差异(P<0.01)。通过心肝肾同调方,失眠女性的更年期症状也有明显的改善,尤其在潮热汗出(χ^(2)=28.613,P=0.000),乏力(χ^(2)=16.470,P=0.000)烦躁(χ^(2)=9.802,P=0.007)等方面具有统计学差异。结论更年期女性的失眠是内外因相互作用,多脏腑失衡的结果。因此,在临证时要分明主症与兼症,分辨心肝肾的失调关系,在遣方用药时要三脏兼顾,随症加减,方能取得良好的疗效。Objective The menopause insomnia women mostly suffer from heart,liver,kidney at the same time,who are fit for three organs treated simultaneously.Methods 210 menopausal women with insomnia were enrolled in different groups to get the effect of treatment and the improvement of symptoms associated with menopause.P<0.05 was considered statistically significant.Results Clinical comparison showed that the total effective rate of sleep improvement was statistically different from that of the control group(P<0.01).Through the heart,liver and kidney coadjustment prescription,the menopausal symptoms of insomnia women also significantly improved,especially in hot flashes,sweating(χ^(2)=28.613,P=0.000),fatigue(χ^(2)=16.470,P=0.000)irritability(χ^(2)=9.802,P=0.007)and other aspects of statistical differences.Conclusion The insomnia of menopausal women is the result of internal and external factors'interaction and the imbalance of multiple viscera.Therefore,A good curative effect will be achieved if clearing the main disease and syndrome and carefully distinguishing the heart,liver and kidney disorders in the clinical symptoms,taking account of the three viscera and the addition and subtraction in the dispatch of drugs were all treated.

关 键 词：心肝肾 同治方 更年期 失眠 队列研究 

分 类 号：R271.9[医药卫生—中西医结合]