铜(I)催化生物质基平台化合物糠醛与直链醇的氧化-缩合反应  

Copper(I)-Catalyzed Aerobic Oxidative Condensation of Biomass-Based Platform Compound Furfurals with Straight-Chain Alcohols

作　　者：师静 郭鹏飞 李蔚 孙海静 孟令武 仝新利[1] Shi Jing;Guo Pengfei;Li Wei;Sun Haijing;Meng Lingwu;Tong Xinli(School of Chemistry and Chemical Engineering,Tianjin University of Technology,Tianjin 300384)

机构地区：[1]天津理工大学化学化工学院,天津300384

出　　处：《有机化学》2022年第3期905-909,共5页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.21878235);天津市研究生科研创新(No.2019YJSS058)资助项目.

摘　　要：作为已实现工业化生产的生物质平台化合物,糠醛的高质化应用研究是当前能源化工领域的热点之一.本工作以廉价易得的铜盐作为催化剂,使用氧气为氧源,实现了糠醛与直链醇的氧化-缩合反应过程.其中,在糠醛与正丙醇进行反应时,糠醛的转化率和主产物3-(2-呋喃基)-2-甲基-2-丙烯醛选择性分别达94%和99%以上.该方法具有反应温度较低、可操作性强和普适性好等优点,通过“一锅法”串联过程实现了糠醛绿色、高效利用.In the face of the continuous consumption of fossil energy and the increasingly serious ecological damage,the synthesis of liquid fuels and high value-added fine chemicals from biomass-derived furfural has become one of the research hotspots in the field of energy and chemical industry.In this work,a highly efficient and selective aerobic oxidative condensation of furfural with straight-chain alcohol is achieved with simple copper(I)chloride as the catalyst.Therein,3-(2-furanyl)-2-methyl-2-acrolein was synthesized by the oxidative condensation reaction of furfural with n-propanol under the mild conditions.As a result,it is found that the conversion of furfural and the selectivity of main product reached 94%and more than 99.9%in the presence of molecular oxygen,respectively.Moreover,the effects of basic additive,reaction time and temperature were further investigated in detail.In addition,oxidative condensation of different substrates was also successfully performed.This catalytic method provides a promising,green and sustainable technology for the valorization of biomass and biomass-based platform compounds.

关 键 词：糠醛 氧化-缩合 卤代铜盐 氧气 

分 类 号：O621.251[理学—有机化学]