糖尿病合并冠心病患者行冠脉搭桥术围术期血糖控制的效果  

Effect of Perioperative Blood Glucose Control in Patients with Diabetes and Coronary Heart Disease Undergoing Coronary Artery Bypass Grafting

作　　者：林玲[1] LIN Ling(Fujian Provincial Hospital,Fuzhou,Fujian Province,350001 China)

机构地区：[1]福建省立医院,福建福州350001

出　　处：《糖尿病新世界》2022年第11期40-43,共4页Diabetes New World Magazine

摘　　要：目的针对糖尿病合并冠心病患者行冠脉搭桥术,并应用胰岛素持续滴注干预措施,观察其干预效果。方法选择2018年6月—2021年6月期间收治的150例糖尿病合并冠心病且行冠脉搭桥术治疗的患者,根据随机数表法分为对照组和研究组,各75例。对照组应用常规口服降糖药物干预,研究组应用胰岛素持续滴注干预,观察两组患者的临床效果,统计对比两组患者的相关指标、并发症发生率、生活质量。结果干预后,研究组糖化血红蛋白(HbAlc)(6.95±0.27)%、空腹血糖(FPG)(7.52±1.53)mmol/L、餐后2 h血糖(2 hPG)(9.17±1.73)mmol/L低于对照组,差异有统计学意义(t=9.331、4.111、2.552,P<0.05);研究组并发症发生率4.00%低于对照组,差异有统计学意义(χ^(2)=4.127,P<0.05);研究组心绞痛发作情况、心绞痛稳定状态、活动受限程度、疾病主观感受、治疗满意度评分(93.67±11.67)分、(84.37±9.80)分、(88.14±9.84)分、(70.63±9.88)分、(88.94±10.12)分优于对照组,差异有统计学意义(t=6.646、6.525、13.190、4.935、6.049,P<0.05)。结论将胰岛素持续滴注干预措施应用于糖尿病合并冠心病患者行冠脉搭桥术治疗之中,可以优化患者的各项血糖相关指标,降低并发症发生率,同时还可以提升患者的生活质量,应用效果良好。Objective To perform coronary artery bypass grafting in patients with diabetes mellitus complicated with coronary heart disease,and apply continuous insulin infusion intervention to observe the intervention effect.Methods From June 2018 to June 2021,150 patients with diabetes complicated with coronary heart disease who underwent coronary artery bypass grafting were selected and divided into control group and study group according to the random number table method,with 75 cases in each group.The control group received routine oral hypoglycemic drug intervention,and the study group received continuous insulin infusion intervention.The clinical effects of the two groups were observed,and the relevant indicators,complication rate and quality of life of the two groups were statistically compared.Results After the intervention,the glycosylated hemoglobin(HbAlc)(6.95±0.27)%,fasting blood glucose(FPG)(7.52±1.53)mmol/L and 2 h postprandial blood glucose(2 hPG)(9.17±1.73)mmol/L in the study group were significantly lower than those in the control group,the difference was statistically significant(t=9.331,4.111,2.552,P<0.05).The incidence of complications in the study group was 4.00%lower than that in the control group,and the difference was statistically significant(χ^(2)=4.127,P<0.05).Angina pectoris attack,stable state of angina pectoris,degree of activity restriction,subjective feeling of disease,treatment satisfaction score,in the study group were(93.67±11.67)points,(84.37±9.80)points,(88.14±9.84)points,(70.63±9.88)points and(88.94±10.12)points,which were better than those in the control group,and the difference was statistically significant(t=6.646,6.525,13.190,4.935,6.049,P<0.05).Conclusion Insulin continuous infusion intervention was applied in the treatment of coronary artery bypass grafting in patients with diabetes and coronary heart disease,can optimize various blood glucose-related indicators of patients,reduce the incidence of complications,and at the same time improve the quality of life of patients.

关 键 词：糖尿病 冠心病 冠脉搭桥术 胰岛素持续滴注 

分 类 号：R76[医药卫生—耳鼻咽喉科]