足月新生儿颅内出血病因研究进展  

Research progress on etiology of intracranial hemorrhage in term neonates

作　　者：吴宇鑫(综述) 翟瑄(审校)[1] WU Yuxin;ZHAI Xuan(Department of Neurosurgery,Affiliated Children’s Hospital of Chongqing Medical University,Chongqing 400014,China)

机构地区：[1]重庆医科大学附属儿童医院神经外科,400014

出　　处：《重庆医学》2022年第13期2331-2335,共5页Chongqing medicine

基　　金：国家自然科学基金面上项目(81971217)。

摘　　要：颅内出血(ICH)是导致新生儿神经系统功能障碍或死亡的重要原因之一。早产儿与足月儿ICH在病因、临床表现、出血部位等方面均有很大不同。早产儿最常见的生发基质出血很少发生在足月儿。超过一半的足月儿ICH找不到明确的原因,目前发现血液系统疾病、脑血管病变、机械性损伤、缺血性脑损伤出血性转化、感染、窒息等其他诱因均可引起ICH,不同原因导致的出血特征不一。了解足月儿与早产儿ICH的差异和出血原因是早期做出正确决策的关键。Intracranial hemorrhage(ICH)is one of important causes of neonatal death or neurological dysfunction.ICH in preterm and term infants differ a lot in etiology,clinical manifestations,bleeding sites and so on.Germinal matrix bleeding,the most common type in preterm neonates,rarely occurs in term neonates.More than half of ICH in term neonates can not find a exact cause.By now,it is found that the diseases of blood system,cerebrovascular disease,mechanical injury,hemorrhagic transformation of ischemic brain injury,infection and asphyxia and other inducements all cause ICH.The bleeding characteristics caused by different reasons are different.Understanding the differences and causes of ICH between term neonates and premature neonates is the key to make the correct decisions in early stage.

关 键 词：新生儿颅内出血 足月儿 早产儿 病因 治疗 

分 类 号：R651[医药卫生—外科学]