低分子肝素钠联合双下肢气压泵在子宫脱垂患者术后预防下肢静脉血栓中的应用价值  

Application value of low molecular weight heparin sodium combined with double lower extremity pneumatic pump in the prevention of lower extremity venous thrombosis in patients with uterine prolapse after operation

作　　者：于峰[1] 李美杰[1] 陈玉[2] Yu Feng;Li Meijie;Chen Yu(Department of Gynaecology,Qingdao Eighth People's Hospital,Qingdao 266100,Shandong,China;Department of General Surgery,Qingdao Eighth People's Hospita,Qingdao 266100,Shandong,China)

机构地区：[1]青岛市第八人民医院妇科,山东青岛266100 [2]青岛市第八人民医院普外科,山东青岛266100

出　　处：《血管与腔内血管外科杂志》2022年第5期617-620,共4页Journal of Vascular and Endovascular Surgery

摘　　要：目的探究低分子肝素钠联合双下肢气压泵在子宫脱垂患者术后预防下肢静脉血栓中的应用价值。方法收集2020年11月至2021年12月于青岛市第八人民医院行盆底手术治疗的100例子宫脱垂患者,按照治疗方法的不同将其分为对照组与观察组,各50例。对照组采用双下肢气压泵治疗,观察组采用双下肢气压泵+低分子肝素钠治疗。比较两组患者治疗前后的双侧股静脉血流速度、凝血功能指标、下肢周径,记录下肢静脉血栓形成情况。结果治疗后,两组患者双侧股静脉流速、下肢周径均高于本组治疗前,观察组患者双侧股静脉流速高于对照组患者,但观察组患者下肢周径低于对照组患者,差异均有统计学意义(P<0.05)。治疗后,观察组患者凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)及凝血酶时间(TT)均长于本组治疗前,且观察组患者PT、APTT、TT均长于对照组患者,差异有统计学意义(P<0.05)。观察组患者下肢静脉血栓发生率为6.00%(3/50),低于对照组的22.00%(11/50),差异有统计学意义(P<0.05)。结论子宫脱垂患者术后接受低分子肝素钠联合双下肢气压泵治疗,可有效改善患者血流速度、下肢周径,调整患者凝血功能指标的同时降低患者发生下肢静脉血栓的可能性,具有较高的临床应用价值。Objective To explore the application value of low molecular weight heparin sodium combined with bilateral lower extremity pneumatic pump in the prevention of lower extremity venous thrombosis in patients with uterine prolapse after the operation.Method A total of 100 patients with uterine prolapse who underwent pelvic floor surgery in Qingdao Eighth People's Hospital from November 2020 to December 2021 were collected and divided into control group and observation group according to the different treatment methods,50 cases in each group.The control group was treated with the bilateral lower extremity air pressure pump,and the observation group was treated with the bilateral lower extremity air pressure pump+low molecular weight heparin sodium.The bilateral femoral venous blood flow velocity,coagulation function index,and lower extremity circumference were compared between the two groups before and after treatment,the venous thrombosis of the lower extremity was also recorded.Result After treatment,the bilateral femoral vein flow velocity and lower extremity circumference of the two groups were higher than those before the treatment in the same group,the bilateral femoral vein flow velocity of the observation group was higher than that of the control group,while the lower extremity circumference of the observation group was lower than that of the control group,the differences were statistically significant(P<0.05).After treatment,the prothrombin time(PT),activated partial thromboplastin time(APTT)and thrombin time(TT)in the observation group were longer than those before the treatment,and the PT,APTT,and TT in the observation group were longer than those in the control group,the differences were statistically significant(P<0.05).The incidence of lower extremity venous thrombosis in the observation group was 6.00%(3/50),lower than 22.00%(11/50)in the control group,the difference was statistically significant(P<0.05).Conclusion Patients with uterine prolapse who receive low molecular weight heparin sodium combined wi

关 键 词：子宫脱垂 低分子肝素钠 双下肢气压泵 下肢静脉血栓 凝血功能 

分 类 号：R543[医药卫生—心血管疾病]