紫外线调控动物皮肤生理状态的研究进展  

Research progress on the regulation of animal skin physiological state by ultraviolet

作　　者：李颖 宋峰 苏德其其格 AKONYANI Zaccheaus Pazamilala 乌兰吐雅 丽春[1] 吴江鸿 LI Ying;SONG Feng;Sudeqiqige;Zaccheaus Pazamilala AKONYANI;Wulantuya;LI Chun;WU Jianghong(College of Animal Science and Technology,Inner Mongolia University for the Nationalities,Tongliao 028000,China;Inner Mongolia Academy of Agricultural&Animal Husbandry Sciences,Hohhot 010031,China)

机构地区：[1]内蒙古民族大学动物科技学院,内蒙古通辽028000 [2]内蒙古自治区农牧业科学院,呼和浩特010031

出　　处：《黑龙江畜牧兽医》2022年第8期34-39,130,共7页Heilongjiang Animal Science And veterinary Medicine

基　　金：国家自然科学基金项目(31560623);国家服务特殊需求蒙药学博士点建设专项开放课题(MDMYBJ2019004);内蒙古自然科学基金项目(2018MS03034,2019MS03078);内蒙古自治区农牧业科学院创新基金项目(2017CXJJM03-2);内蒙古民族大学博士启动基金项目(BS527)。

摘　　要：紫外线(ultraviolet,UV)是位于光谱中紫色光之外的射线,为不可见光,照射动物体后会诱导动物机体产生一系列的生理变化,影响动物的生物节律。畜牧业生产中,家畜的生产性能大多数具有年节律或季节性节律,且UV的节律性变化对动物皮肤的生理状态有影响。皮肤是动物内外环境交互的屏障,皮肤细胞的周期、增殖和凋亡与生物钟紧密地交织在一起。文章综述了UV对皮肤相关基因的表达调控,以及对DNA结构、基因转录、蛋白质翻译、Wnt信号通路的影响等方面的研究进展,分析UV影响动物组织-细胞-基因的分子调控网络来维持动物皮肤生理状态的机制,探讨利用紫外线调控家畜生产性能的可行性,同时为研究UV如何调控动物皮肤生理状态奠定坚实的理论基础。Ultraviolet(UV), which is invisible is a ray located outside the purple light in the spectrum. Exposure to UV light will induce a series of physiological changes in the animal body and affect its biological rhythm. In livestock production, most of the livestock production performance has annual or seasonal rhythm, and the rhythmic change of UV has an effect on the physiological state of animal skin. The skin is the barrier between the animal’s internal and external environment. The cycle, proliferation and apoptosis of skin cells are closely intertwined with the biological clock. The research progress of UV on skin-related gene expression regulation, DNA structure, gene transcription, protein translation and Wnt signaling pathway were reviewed. The mechanisms of UV maintaining physiological state of animal skin by affecting molecular regulatory network of animal tissue-cell-gene were analyzed, and the feasibility of using UV to regulate the production performance of livestock was explored, aiming to lay a solid theoretical foundation for how UV regulates physiological state of animal skin.

关 键 词：皮肤 紫外线 基因 信号通路 季节节律 生物节律 

分 类 号：S815[农业科学—畜牧学]