2016—2020年辽宁省土源性线虫感染现状及流行趋势  

Surveillance and trends of soil-transmitted helminth infections in Liaoning Province,2016—2020

作　　者：于维君[1,2] 王子江 王博[1] 毛玲玲[1] 吴琪俊[2] 姚文清[1] 孙英伟[1] YU Wei-jun;WANG Zi-jiang;WANG Bo;MAO Ling-ling;WU Qi-jun;YAO Wen-qing;SUN Ying-wei(Liaoning Provincial Center for Disease Control and Prevention,Shenyang 110005,China;Shengjing Hospital of China Medical University,Shenyang 110004,China)

机构地区：[1]辽宁省疾病预防控制中心,沈阳110005 [2]中国医科大学附属盛京医院,沈阳110004

出　　处：《中国寄生虫学与寄生虫病杂志》2022年第2期211-215,222,共6页Chinese Journal of Parasitology and Parasitic Diseases

基　　金：“十三五”国家科技重大专项(2017ZX10103007)。

摘　　要：目的了解辽宁省土源性线虫感染现状及流行趋势,为制定土源性线虫病防治规划、策略和措施提供科学依据。方法2016—2020年辽宁省根据《全国肝吸虫病和土源性线虫病监测方案(试行)》和实施细则要求开展监测工作。每年每市选择1个县(市、区)作为监测点。监测点按地理方位划分为东、西、南、北、中等5个片区,每个片区抽取1个乡(镇、街道)的1个行政村(社区)开展监测工作,每个行政村(社区)整群抽取3周岁以上居民200人。采集监测对象粪样(>30 g),采用改良加藤厚涂片法(一粪二检)检测虫卵,虫卵计数并计算虫种感染率和感染度。钩虫卵阳性者采用试管滤纸培养法鉴定钩虫种类。3~9周岁儿童加做透明胶纸肛拭法检测蛲虫卵。每个行政村(社区)随机抽取5户家庭,每户采集1份田地或菜园的土样≥400 g,其中350 g用于钩蚴监测,50 g用于人蛔虫卵监测。率的比较采用χ^(2)检验。结果2016—2020年全省14个市,共设置70个监测点,共调查69909人,其中儿童4659人。土源性线虫总感染率为0.26%(184/69909),蛔虫和鞭虫感染率分别为0.25%(178/69909)和0.01%(6/69909),未检出钩虫和蛲虫。2016—2020年人群土源性线虫感染率分别为0.59%(89/15097)、0.19%(28/14554)、0.27%(33/12044)、0.13%(19/14103)、0.11%(15/14111),不同年份差异有统计学意义(χ^(2)=59.44,P<0.01)。丹东市土源性线虫感染率最高,为1.77%(89/5042),其次为大连市0.56%(28/5004)和本溪市0.42%(23/5451);男性土源性线虫感染率为0.26%(90/34852),女性为0.27%(94/35057),二者差异无统计学意义(χ^(2)=0.07,P>0.05);60~69岁年龄组感染率最高,为0.36%(50/13803),其次为40~49岁年龄组(0.32%,34/10788)和70岁及以上年龄组(0.31%,23/7396),各年龄组间差异有统计学意义(χ^(2)=18.30,P<0.01);仅在满族与汉族人群中检出土源性线虫,感染率分别为0.55%(97/17643)、0.17%(87/51154),二者差异有统计学意义(χ^(2)=75.04,P<0.01);Objective To investigate the prevalence and transmission of soil-transmitted helminth(STH)in Liaoning Province,in order to provide scientific evidence for development of control plans,strategies and measures a-against these diseases in Liaoning Province.Methods The surveillance was performed during 2016—2020 in Liaoning Province according to the National Surveillance Program and Implementation Guideline for Chlonorchiasis and Soil-transmitted Helminthiasis.One county(city or district)per provincial city was selected annually as a surveillance site.Each surveillance site was further divided 5 regions as geographical east,west,south,north and centre.One village was chosen from each region to conduct surveillance,and 200 permanent residents over 3 years old were randomly enrolled from each village.Fecal samples(>30 g)from enrolled residents were collected and were examined for STH eggs(two slide-reading for each sample)using the modified Kato-Katz thick smear method to estimate infection rate and intensity.The samples that are positive for hookworm eggs were further examined by test-tube filter paper incubation for the larva to identify the species.Cellophane anal swab method was used to detect Enterobius vermicularis eggs in children aged 3-9 years.The contamination of Ascaris eggs and hookworm larvae was also monitored in soil samples collected from 5 households in each village.Chi-square test was used to compare the infection rates.Results Total 69909 people were recruited from 70 surveillance sites in Liaoning Province during2016—2020,including 4659 children aged 3-9,and the overall infection rate of STH infection was 0.26%(184/69909),and the infection rate of A.lumbricoides and Trichuris trichiura were 0.25%(178/69909)and 0.01%(6/69909),respectively.Hookworm and E.vermicularis were not detected.The STH infection rate in the residents from 2016—2020respectively were 0.59%(89/15097),0.19%(28/14554),0.27%(33/12044)),0.13%(19/14103),and 0.11%(15/14111)(χ^(2)=59.44,P<0.01).The top three cities with the highes

关 键 词：土源性线虫 感染 监测 辽宁省 

分 类 号：R532.1[医药卫生—内科学]