免疫功能健全者获得性弓形虫病的研究进展  

Research progress on acquired toxoplasmosis in immunocompetent individuals

作　　者：赵紫琪 吕芳丽[2,3,4] ZHAO Zi-qi;LV Fang-li(Artemisinin Research Center,Guangzhou University of Chinese Medicine,Guangzhou 510405,China;Department of Clinical Laboratory,The Seventh Affiliated Hospital,Sun Yat-sen University,Shenzhen 518107,China;Department of Parasitology,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou 510080,China;Key Laboratory of Tropical Disease of Ministry of Education,Sun Yat-sen University,Guangzhou 510080,China)

机构地区：[1]广州中医药大学青蒿研究中心,广州510405 [2]中山大学附属第七医院检验科,深圳518107 [3]中山大学中山医学院寄生虫学教研室,广州510080 [4]中山大学热带病防治研究教育部重点实验室,广州510080

出　　处：《中国寄生虫学与寄生虫病杂志》2022年第2期228-235,共8页Chinese Journal of Parasitology and Parasitic Diseases

基　　金：国家自然科学基金面上项目(81971955);广东省自然科学基金面上项目(2019A1515011667,2021A1515012115);广东省研究生教育创新计划项目(2021SFKC003);广东省科技计划项目(2021A0505030060)。

摘　　要：免疫功能健全者感染刚地弓形虫(简称弓形虫)后多数表现为无症状,但少数可出现轻微甚至严重的临床症状。笔者在PubMed和中国知网中使用关键词“免疫功能健全”“弓形虫”“弓形虫病”“诊断”和“治疗”系统检索1984—2021年报道的免疫功能健全的获得性弓形虫病病例文献,综述了免疫功能健全者获得性弓形虫病的临床表现、发病机制、诊断和治疗等方面的资料,为临床上鉴别诊断和治疗弓形虫病提供参考。Although Toxoplasma gondii infection is usually asymptomatic in immunocompetent individuals,a small part of T.gondii-infected immunocompetent individuals may have mild or even severe clinical symptoms.Using the keywords“immunocompetent”“T.gondii”“toxoplasmosis”“diagnosis”and“treatment”in the PubMed and China National Knowledge Infrastructure(CNKI)search engines,the authors systematically searched the cases of acquired toxoplasmosis in immunocompetent individuals reported from 1984 to 2021.This review summarizes the clinical manifestation,pathogenesis,diagnosis,and treatment of acquired toxoplasmosis in immunocompetent individuals,to provide a reference for clinical differential diagnosis and treatment of toxoplasmosis.

关 键 词：弓形虫病 免疫功能健全者 诊断 治疗 

分 类 号：R531.8[医药卫生—内科学]