Neuroform,Atlas支架辅助弹簧圈栓塞治疗颅内宽颈动脉瘤的临床研究  

Neuroform Atlas stent-assisted coil embolization in treatment of intracranial wide-necked aneurysms

作　　者：余舰 高歌 陈昱[1] 顾大群 晁迎九 张扬[1] 牛朝诗 Yu Jian;Gao Ge;Chen Yu;Gu Daqun;Chao Yingjiu;Zhang Yang;Niu Chaoshi(Department of Neurosurgery,First Affiliated Hospital of University of Science and Technology of China(Provincial Hospital of Anhui Province),Hefei 230001,China)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院)神经外科,合肥230001

出　　处：《中华神经医学杂志》2022年第5期474-477,共4页Chinese Journal of Neuromedicine

基　　金：安徽省重点研究与开发计划(202104J07020046)。

摘　　要：目的观察Neuroform Atlas支架辅助弹簧圈栓塞治疗颅内宽颈动脉瘤的短期效果及并发症,初步探讨其安全性和有效性。方法回顾性分析中国科学技术大学附属第一医院神经外科自2020年9月至2021年8月收治的33例颅内宽颈动脉瘤患者的临床资料,所有患者均采用Neuroform Atlas支架辅助弹簧圈栓塞治疗,其中单支架28例,双支架5例。使用Raymond分级评估术后即刻动脉瘤栓塞程度。术后3~6个月时采用改良Rankin量表(mRS)评分评估患者预后,同时行DSA复查以了解动脉瘤有无复发及载瘤动脉通畅情况。结果术后即刻复查DSA示所有动脉瘤均致密栓塞(RaymondⅠ级)。1例患者出现术中血栓形成,予替罗非班溶栓后血流恢复,术后未出现新发神经功能障碍。术后3~6个月时所有患者均预后良好;21例(63.6%)患者完成DSA复查,示载瘤动脉无狭窄或血栓形成,动脉瘤无复发。结论Neuroform Atlas支架辅助弹簧圈栓塞治疗颅内宽颈动脉瘤疗效好且安全性高。Objective To observe the short-term efficacy and complications of intracranial wide-necked aneurysms treated by Neuroform Atlas stent-assisted coil embolization,and preliminary explore its safety and effectiveness.Methods A retrospective analysis was performed.The clinical data of 33 patients with intracranial wide-necked aneurysms,admitted to our hospital from September 2020 to August 2021,were collected.All patients underwent Neuroform Atlas stent-assisted coil embolization,including 28 patients with single stent assisted coil embolization and 5 with double stent assisted embolization.Raymond grading was used to evaluate the degrees of immediate postoperative aneurysm embolization.Modified Rankin scale(mRS)was used to assess the prognoses 3-6 months after surgery.DSA was performed to recheck the recurrence of aneurysms and the patency of the parent artery.Results DSA immediately after surgery showed that all aneurysms were tightly embolized(Raymond grading I).One patient developed intraoperative thrombosis,and blood flow was restored after tirofiban thrombolytic therapy,without new neurological dysfunction after surgery.Three-6 months after surgery,all patients had a good prognosis;DSA recheck was completed in 21 patients(63.6%),and no stenosis or thrombosis were found in the parent artery and no aneurysm recurrence was noted.Conclusion The Neuroform Atlas stent-assisted coil embolization in treatment of intracranial wide-necked aneurysms has good efficacy and high safety.

关 键 词：颅内动脉瘤 宽颈 Neuroform Atlas支架 栓塞 

分 类 号：R651.12[医药卫生—外科学]