miRNA遗传多态性影响畜禽复杂性状的研究进展  

Research Progress on the Influence of miRNA Genetic Polymorphisms on Complex Traits of Livestock and Poultry

作　　者：余乃祥 谢新科 昌小龙 麻骏武[1] YU Naixiang;XIE Xinke;CHANG Xiaolong;MA Junwu(State Key Laboratory of Pig Genetic Improvement and Production Technology,Jiangxi Agricultural University,Jiangxi Nanchang 330045,China)

机构地区：[1]江西农业大学省部共建猪遗传改良与养殖技术国家重点实验室,江西南昌330045

出　　处：《中国畜牧杂志》2022年第6期65-72,共8页Chinese Journal of Animal Science

基　　金：国家自然科学基金项目(31872339、31790413);国家重点研发计划课题(2018YFD0500401)。

摘　　要：microRNA(miRNA)是基因表达调控网络的重要组成部分,其遗传多态性可能会影响miRNA的表达和功能,进而导致疾病发生或表型变异。本文就miRNA基因启动子、种子区、前体和初级miRNA上的遗传多态性影响畜禽生长、胴体、繁殖和肉质等复杂性状进行综述,并探讨了前沿的研究方向,以期有助于解析畜禽重要复杂性状的形成机理和开发育种分子标记。MicroRNAs(miRNAs) are an important part of the gene expression regulation network, and their genetic polymorphisms may affect the expression and function of miRNAs, leading to disease occurrence or phenotypic variation.This paper reviews the effects of genetic polymorphisms in miRNA gene promoters, seed regions, precursors, and primary miRNAs on complex traits of livestock and poultry including growth, carcass, reproduction, and meat quality, and discusses cutting-edge research directions, in order to understand the formation mechanism of important complex traits in livestock and poultry and to develop molecular markers for breeding.

关 键 词：MIRNA 多态性 畜禽 复杂性状 SNP 

分 类 号：S813.1[农业科学—畜牧学]