卵巢子宫内膜异位症术后地诺孕素结合体质辩证调理辅助疗效及对患者卵巢功能影响  

Clinical efficacy of dienogest combined with physical constitution dialectical conditioning for treating patients with ovarian endometriosis operation and its effect on postoperative ovarian function

作　　者：李倩[1] 谈海东[1] 潘晓微[1] LI Qian;TAN Haidong;PAN Xiaowei(Nanhai District Materity and Child Health care Hospital of Foshan Ciry,Guangdong Province,528200)

机构地区：[1]广东省佛山市南海区妇幼保健院,528200

出　　处：《中国计划生育学杂志》2022年第7期1520-1524,共5页Chinese Journal of Family Planning

基　　金：2020年佛山市自筹经费类科技计划项目(2020001004297)。

摘　　要：目的:探究地诺孕素结合体质辩证调理对腹腔镜下卵巢子宫内膜异位症手术术后效果及对患者卵巢功能影响.方法:选择2019年1月-2021年8于本院行卵巢子宫内膜异位症腹腔镜手术治疗患者84例,随机分为两组各42例,均行常规腹腔镜下囊肿剥除术并术后给予地诺孕素治疗,观察组结合体质辩证调理治疗.分析比较两组治疗效果、体质改善情况、疼痛数字评分(NRS)、卵巢功能(卵泡发育、雌二醇、促黄体生成素、促卵泡刺激素)、不良反应、随访6个月复发情况.结果:观察组治疗总有效率(97.6%)高于对照组(78.6%)(P<0.05);两组均出现腹痛、阴道不规则出血,对症治疗后均缓解,随访期间观察组复发率(2.4%)小于对照组(19.1%)(P=0.029).治疗后观察组体质改善程度优于对照组,NRS评分(3.64±0.49分)、卵泡发育萎缩(2.4%)、卵泡黄素化(4.8%)、性激素水平均低于对照组(5.21±0.61分、23.8%、21.4%)(均P<0.05).结论:地诺孕素结合体质辩证调理可显著提升卵巢子宫内膜异位症术后治疗效果,可减小患者痛经并改善体质及卵巢功能,降低复发.Objective: To investigate the clinical effect of dienogest combined with physical constitution dialectical conditioning for treating patients with ovarian endometriosis operation, and to study its effect on postoperative ovarian function of the patients. Methods: A total of 84 patients who wanted laparoscopic surgery for treating ovarian endometriosis were selected and randomly divided into two groups(42 patients in each group) from January 2019 to August 2021. The patients in both groups were given conventional laparoscopic excision of ovarian endometriosis. The patients in the control group were given dienogest after operation, and the patients in the observation group were given dienogest combined with constitution dialectical conditioning after operation. The treatment effect and physical improvement, the pain degree by numeric rating score(NRS), the levels of ovarian function indexes, such as follicular development status, and the levels of estradiol(E), luteinizing hormone(LH), and follicle stimulating hormone(FSH), and the adverse reactions rate of the patients were analyzed and compared between the two groups. The recurrence situations of ovarian endometriosis of the patients in the two groups were followed up for 6 months. Results: The total effective rate(97.6%) of the patients in the observation group was significantly higher than that(78.6%) of the patients in the control group(P<0.05). The patients with abdominal pain and irregular vaginal bleeding occurred in both groups, and which were relieved after symptomatic treatment. The recurrence rate(2.4%) of ovarian endometriosis of the patients in the observation group during followed up was significantly lower than that(19.1%) of the patients in the control group(P=0.029). After treatment, the physical constitution improvement of the patients in the observation group was significantly better than that of the patients in the control group.NRS score(3.64±0.49points),the rates of follicular development atrophy(2.4%)and follicular luteinization(4.8%)of the

关 键 词：卵巢子宫内膜异位症 腹腔镜术后 地诺孕素 体质辩证调理 卵巢功能 复发 

分 类 号：R713.4[医药卫生—妇产科学]