活血化瘀方灌肠辅助手术治疗输卵管梗阻性不孕效果  

Curative effect of surgery assisted by Huoxue huayu decoction enema for treating patients with infertility caused by tubal obstruction

作　　者：尹辉 YIN Hui(Boxhou Traditional Chinese Medicine Hospital,Boxhou,Anhui Province,236800)

机构地区：[1]安徽省亳州市中医院,236800

出　　处：《中国计划生育学杂志》2022年第7期1539-1542,1547,共5页Chinese Journal of Family Planning

摘　　要：目的:探讨活血化瘀方灌肠辅助手术治疗气滞血瘀证输卵管梗阻性不孕症效果.方法:选取2018年1月-2021年4月本院收治的输卵管梗阻性不孕患者98例,简单随机分组为观察组与对照组各49例,均予以输卵管介入腹腔镜下再通术治疗,观察组术后应用活血化瘀方灌肠治疗3个疗程.比较治疗后两组临床疗效及中医证候评分,检测全血高切黏度(HBV)、全血低切黏度(LBV)与血浆黏度(PV).结果:持续治疗3个月经周期,观察组总有效率(93.9%)与对照组(87.8%)无差异(P>0.05),两组下腹疼痛、带下偏多、神疲乏力中医证候评分均低于治疗前且观察组低于对照组,两组治疗后HBV、LBV、PV均低于治疗前且观察组低于对照组(均P<0.05);治疗后6个月,观察组妊娠成功率(81.6%)高于对照组(63.3%)(P<0.05).结论:输卵管梗阻性不孕症采用活血化瘀方灌肠辅助手术治疗可降低患者中医证候评分及血流动力学水平,提高术后临床妊娠率.Objective: To explore the curative effect of surgery assisted by Huoxue huayu decoction enema for treating patients with infertility caused by tubal obstruction of qi-stagnation and blood-stasis syndrome. Methods: A total of 98 patients with tubal obstructive infertility who had undergone laparoscopic fallopian tube recanalization were enrolled and were divided into observation group and control group(49 cases in each group) according to simple random grouping method between January 2018 and April 2021. The patients in the observation group were additionally treated with Huoxue huayu decoction enema for 3 courses of treatment. The clinical curative effect and scores of TCM syndromes of the patients after treatment were compared between the two groups. The values of high blood viscosity(HBV), low blood viscosity(LBV), and plasma viscosity(PV) of the patients in the two groups were detected. Results: There was no significant difference in the total effective rate(93.9% vs. 87.8%) of the patients between the two groups(P>0.05). The TCM syndrome scores of lower abdominal pain, vaginal bleeding, and fatigue of the patients in the two groups had decreased significantly after treatment, and which of the patients in the observation group were significantly lower than those of the patients in the control group. The values of HBV, LBV and PV of the patients in the two groups had decreased significantly after treatment, and which of the patients in the observation group were significantly lower than those of the patients in the control group(all P<0.05). In the 6 th month after treatment, the success rate of pregnancy(81.6%) of the patients in the observation group was significantly higher than that(63.3%) of the patients in the control group(P<0.05). Conclusion: Surgery assisted by Huoxue huayu decoction for treating patients with infertility caused by tubal obstruction can reduce their scores of TCM syndromes and hemodynamic level, and can increase their clinical pregnancy rate after surgery.

关 键 词：输卵管梗阻性不孕症 输卵管介入腹腔镜下再通术 活血化瘀方 全血高切黏度 全血低切黏度 血浆黏度 中医证候评分 妊娠率 

分 类 号：R713.7[医药卫生—妇产科学]