宫腔粘连分离术后应用胎盘组织液预防再粘连效果  

Effect of placental tissue fluid for preventing postoperative intrauterine readhesion of patients after intrauterine adhesion separation

作　　者：朱天垣 谢秀英[2] 蒲雯婕 康筱珊[4] ZHU Tianyuan;XIE Xiuying;PU Wenjie;KANG Xiaoshan(Gansu Maternai and Child Health Care Hospital,Lanzhou,Gansu Province,730050;The Second Affiliated Hospital of Xi'an Jiaotong University;Northuestern University for Nationalities;Lanzhou Maternal and Child Health Care Hospital)

机构地区：[1]甘肃省妇幼保健院,兰州730050 [2]西安交通大学第二附属医院 [3]西北民族大学 [4]兰州市妇幼保健院

出　　处：《中国计划生育学杂志》2022年第7期1548-1550,1554,共4页Chinese Journal of Family Planning

摘　　要：目的:探究胎盘组织液预防宫腔粘连术后再粘连效果.方法:选择2016年1月-2018年1月本院治疗的宫腔粘连患者118例,按照随机分组原则分为观察组(62例)及对照组(56例),宫腔镜分离术后均使用补佳乐+黄体酮胶丸人工周期治疗3个月,观察组同时给予胎盘组织液治疗3个月.比较两组月经及宫腔恢复情况,随访1年妊娠情况以及随访3年统计宫腔粘连再发生情况.结果:观察组月经恢复总有效率(98.2%)、宫腔恢复总有效率(98.2%)高于对照组(71.0%、85.5%),妊娠率(21.4%)高于对照组(8.1%),粘连再发生率(8.1%)低于对照组(25.4%)(均P<0.05).结论:宫腔镜下宫腔粘连分离术后,人工周期治疗基础上应用胎盘组织液治疗对预防术后宫腔再粘连效果提高,有利于宫腔恢复和提高术后妊娠率.Objective: To study the effect of placental tissue fluid for preventing postoperative intrauterine readhesion of patients after intrauterine adhesion separation. Methods: 118 patients with intrauterine adhesion were selected and were divided into two groups in accordance with the random principle between January 2016 and January 2018. 62 patients in study group were given placental tissue fluid combined with estradiol valerate and progestin capsule for 3 months, and 56 patients in control group were given estradiol valerate and progestin capsule for 3 months. The situations of menstrual recovery and uterine recovery of the patients were compared between the two groups. Results: The total effective rate of menstrual recovery(98.2%), uterine recovery(98.2%), and the pregnancy rate(21.4%) of the patients in the study group were significantly higher than those(71.0%, 85.5%, and 8.1%) of the patients in the control group. The rate of intrauterine readhesion(8.1%) of the patients in the study group was significantly lower than that(25.4%) of the patients in the control group(all P<0.05). Conclusion: After hysteroscopic separation of intrauterine adhesions, the treatment by placental tissue fluid combined with the artificial menstrual cycles has better effect on preventing the postoperative intrauterine readhesions, and which is conducive to the recovery of uterine cavity and to the improvement of the postoperative pregnancy rate.

关 键 词：宫腔粘连 宫腔粘连分离术 胎盘组织液 人工周期 治疗效果 复发 妊娠 

分 类 号：R713.4[医药卫生—妇产科学]