Malondialdehyde and superoxide dismutase levels of dogs with complex dermatitis after trigona honey therapy  

作　　者：Ni Luh Lasmi Purwanti I Nyoman Suartha I Nyoman Suarsana Putu Devi Jayanti 

机构地区：[1]Master Student of Veterinary Medicine,Faculty of Veterinary Medicine,Udayana University,Jl.PB.Sudirman,Dangin Puri Klod,Denpasar,Bali 80234,Indonesia [2]Laboratory of Internal Medicine,Faculty of Veterinary Medicine,Udayana University,Jl.PB.Sudirman,Dangin Puri Klod,Denpasar,Bali 80234,Indonesia [3]Laboratory of Biochemistry,Faculty of Veterinary Medicine,Udayana University,Jl.PB.Sudirman,Dangin Puri Klod,Denpasar,Bali 80234,Indonesia

出　　处：《Infectious Diseases Research》2022年第2期32-37,共6页传染病研究（英文）

摘　　要：Dermatitis is a combination of various skin disease agents such as bacteria,fungi,ectoparasites,viruses and metabolic diseases with various clinical symptoms or signs.Dermatitis can cause an imbalance between ROS and antioxidants.Exogenous antioxidants are needed to help balance antioxidant and ROS levels in the body by providing trigona honey.This study aims to determine the MDA and SOD levels of dogs with complex dermatitis after administration of trigona honey.This study used 12 dogs with complex dermatitis,with a moderate severity score.Dogs 4-6 months old.Samples were divided into control group(P0)without honey,fresh honey group(P1)5 mL/head/day and capsule honey group(P2)0.1 mg/head/day.Honey was given for 4 weeks in the treatment group.Examination of MDA and SOD levels was carried out using the ELISA kit.The results showed that the Trigona honey treatment had a significant effect(P<0.05)in reducing MDA levels and increasing SOD levels in dogs with complex dermatitis.Duncan's test results showed that SOD levels increased significantly at week 4,while week 2 and week 0 did not increase significantly.Trigona honey has anti-inflammatory,antibacterial,antiaging,antiulcer effects,helps in wound healing dermatitis and is an antioxidant.So that trigona honey can reduce plasma MDA levels and increase plasma SOD levels in dogs with complex dermatitis.

关 键 词：MDA levels SOD levels complex dermatitis trigona honey 

分 类 号：R28[医药卫生—中药学]