输血前患者不规则抗体检测结果分析及其临床意义  

Results and clinical significance of irregular antibody test before blood transfusion

作　　者：李艳珍 李文秀 Li Yanzhen;Li Wenxiu(Department of Blood Transfusion,the Second People’s Hospital of Shanxi Province,Taiyuan 030012,China)

机构地区：[1]山西省第二人民医院输血科,太原030012

出　　处：《中国实用医刊》2022年第8期23-25,共3页Chinese Journal of Practical Medicine

摘　　要：目的探讨输血前患者不规则抗体检验的临床意义。方法抽取山西省第二人民医院2018年5月至2020年5月收治的1000例计划输血和手术备血患者,筛查其不规则抗体,观察不规则抗体的阳性率及分布情况,分析Rh五项对不规则抗体检出率的影响。结果1000例输血患者筛查出阳性患者120例,阳性率为12.00%。特异性抗体中,Rh系统最多,占37.50%(45/120),自身抗体占15.83%(19/120),无特异性抗体占12.50%(15/120)。Rh五项分型结果显示,不规则抗体筛查中CCDee表型最多,占18.33%(22/120),其次为CcDEe表型(16.67%,20/120)和CcDee表型(15.83%,19/120);RhC、c、D、E、e抗原分析结果显示,RhC抗原阴性患者占8.33%(10/120),Rhc抗原阴性患者占52.50%(63/120),RhE抗原阴性患者占55.83%(67/120),Rhe抗原阴性患者占3.33%(4/120),RhD抗原阴性患者占0.83%(1/120),P<0.05。结论输血患者在输血前进行不规则抗体检验的效果较理想,还可预防输血过程中出现的溶血反应等并发症,减少医疗事故的发生,利于改善患者预后。Objective To investigate the clinical significance of irregular antibody tests before blood transfusion.Methods One thousand blood transfusion patients admitted to the Second People’s Hospital of Shanxi Province from May 2018 to May 2020 were selected,and the irregular antibodies were screened.The production and distribution of irregular antibodies were compared,and the effects of Rh five items test on the detection rate of irregular antibodies were analyzed.Results One hundred and twenty positive patients were screened out from 1000 blood transfusion patients,and the positive rate was 12.00%.Among the specific antibodies,antibodies of Rh system was the most,accounting for 37.50%(45/120),autoantibodies accounted for 15.83%(19/120),non-specific antibodies accounted for 12.50%(15/120).The results of Rh five items test showed that CCDee phenotype was the most in irregular antibody screening,accounting for 18.33%(22/120),followed by CcDEe phenotype(16.67%,20/120)and CcDee phenotype(15.83%,19/120).The results of RhC,c,D,E and e antigen analysis showed that,RhC antigen negative patients accounted for 8.33%(10/120),Rhc antigen negative patients accounted for 52.50%(63/120),RhE antigen negative patients accounted for 55.83%(67/120),Rhe antigen negative patients accounted for 3.33%(4/120),and RhD antigen negative patients accounted for 0.83%(1/120),P<0.05.Conclusions The effect of irregular antibody test before blood transfusion is ideal.It can prevent hemolytic reaction and other complications in the process of blood transfusion,reduce the occurrence of medical accidents,and improve the prognosis of patients.

关 键 词：输血 不规则抗体 血液检验 检验结果 

分 类 号：R457.1[医药卫生—治疗学] R446.6[医药卫生—临床医学]