老年慢性阻塞性肺疾病患者血压变异性与低氧血症发生的相关性  

Correlation between Blood Pressure Variability and Hypoxemia in Older Patients with Chronic Obstructive Pulmonary Disease

作　　者：谢小兵[1] 高云[1] 牛灵[1] 凌敏[1] 苟安栓[1] 哈依那 Xie Xiaobing;Gao Yun;Niu Ling;Ling Min;Gou Anshuan;Ha Yi’na(People’s Hospital of Xinjiang Uygur Autonomous Region,Uramqi 830001)

机构地区：[1]新疆维吾尔自治区人民医院,乌鲁木齐830001

出　　处：《国际老年医学杂志》2022年第4期425-428,共4页International Journal of Geriatrics

基　　金：新疆维吾尔自治区自然科学基金项目(2018D01C235)。

摘　　要：目的观察老年慢性阻塞性肺疾病血压变异性与低氧血症发生的关系。方法回顾性选取2018年2月~2019年10月完成治疗的136例老年慢性阻塞性肺疾病患者作为观察组,收集同期完成治疗的非慢性阻塞性肺疾病老年患者134例作为对照组,记录两组患者血压,计算血压变异系数;依据低氧血症发生情况将观察组分为发生组(55例)与未发生组(81例),对比分析两组血压变异系数,分析血压变异系数与老年慢性阻塞性肺疾病患者合并低氧血症的关系。结果观察组收缩压变异系数、舒张压变异系数均高于对照组(P<0.05);受试者工作特征曲线结果显示,收缩压变异系数、舒张压变异系数预测老年慢性阻塞性肺疾病患者低氧血症发生的曲线下面积分别是0.832、0.810。结论老年慢性阻塞性肺疾病患者发生低氧血症可能受血压变异性的影响,临床可考虑通过观察血压变异性预测低氧血症风险并指导治疗。Objective To observe the relationship between the blood pressure variability and the occurrence of hypoxemia in older patients with chronic obstructive pulmonary disease(COPD).Methods A total of 136 older patients with COPD who completed treatment from February 2018 to October 2019 were assigned to the observation group,and 134 older patients without COPD who completed treatment during the same period were assigned to the control group.The blood pressure was recorded,and the coefficient of variation of blood pressure was calculated.The observation group was subdivided into the hypoxemia group(55 cases)and non-hypoxemia group(81 cases).The coefficient of variation of blood pressure was compared between the two groups;the relationship between coefficient of variation of blood pressure and hypoxemia in older patients with COPD was analyzed.Results The coefficient of variation of systolic and diastolic blood pressure in the observation group were higher than those in the control group(P<0.05).Receiver operating characteristic(ROC)curve showed that area under the curve(AUC)of the coefficient of variation of systolic and diastolic blood pressure to predict the risk of hypoxemia were 0.832 and 0.810,respectively in older patients with COPD.Conclusion Hypoxemia in older patients with COPD may be affected by blood pressure variability.Clinically,it can be considered to predict the risk of hypoxemia and guide treatment by observing blood pressure variability.

关 键 词：慢性阻塞性肺疾病 低氧血症 血压变异性 相关性 

分 类 号：R563.9[医药卫生—呼吸系统]