ERAS对肝外胆管结石患者术后早期炎症反应的影响  

Effect of ERAS on early postoperative inflammatory response in patients with extra-hepatic cholangiolithiasis

作　　者：韩绍伟 周玖桥 李季男 李珍发 HAN Shaowei;ZHOU Jiuqiao;LI Jinan;LI Zhenfa(Hepatobiliary Surgery,Hengyang Central Hospital,Hengyang 421001,Hunan,China;Clinical Laboratory,Hengyang Central Hospital,Hengyang 421001,Hunan,China)

机构地区：[1]衡阳市中心医院肝胆外科,湖南省衡阳市421001 [2]衡阳市中心医院检验科,湖南省衡阳市421001

出　　处：《中南医学科学杂志》2022年第5期696-698,739,共4页Medical Science Journal of Central South China

基　　金：湖南省卫生计生委科研计划一般项目(B2017162)。

摘　　要：目的 探讨加速康复外科(ERAS)对肝外胆管结石患者术后早期炎症反应的影响。方法 将90例行腹腔镜胆囊切除术+胆总管切开取石+T管引流术患者按围手术期的处理方法不同分为ERAS组和对照组。比较两组患者围手术期炎症指标及疗效。结果 两组患者术后炎症指标水平较术前升高,但ERAS组炎症指标升高的程度低于对照组(P<0.05)。ERAS组术后排气、排便时间早于对照组,住院天数、恶心呕吐发生率、术后疼痛强度均低于对照组(P<0.05)。结论 加速康复外科能减轻术后早期炎症反应的发生,有利于患者的康复。Aim To explore the effect of enhanced recorvery after surgery(ERAS)on early postoperative inflam-matory response in patients with extrahepatic cholangiolithiasis.Methods:Ninety patients who underwent laparoscopic cholecystectomy+choledocholithotomy+T tube drainage were divided into ERAS group and control group according to dif-ferent perioperative management methods.Perioperative inflammatory indexes and efficacy were compared between the two groups.Results:The levels of inflammatory indexes in the two groups after surgery were higher than those before sur-gery,but the degree of inflammatory indexes in the ERAS group was lower than that in the control group(P<0.05).The time of postoperative exhaust and defecation in the ERAS group was earlier than that in the control group,and the days of hospitalization,the incidence of nausea and vomiting,and the intensity of postoperative pain were lower than those in the control group(P<0.05).Conclusion ERAS can reduce the occurrence of early postoperative inflammatory response,which is beneficial to the rehabilitation of patients.

关 键 词：加速康复外科 肝外胆管结石 围手术期 炎症反应 

分 类 号：R657.42[医药卫生—外科学]