Logistic多元回归分析复发性泌尿系结石患者的结石成分改变特征及其影响因素  

Logistic Multiple Regression Analysis of the Characteristics and Influencing Factors of Stone Composition in Patients with Recurrent Urinary Calculi

作　　者：梁紫积 陈楚义[1] LIANG Ziji;CHEN Chuyi(Department of Urology,The Second Affiliated Hospital,School of Medicine,The Chinese University of Hong Kong,P.R.China&Longgang District People's Hospital of Shenzhen,Shenzhen,Guangdong,518000)

机构地区：[1]深圳市龙岗区人民医院香港中文大学(深圳)医学院附属第二医院,广东深圳518000

出　　处：《智慧健康》2022年第17期29-32,共4页Smart Healthcare

摘　　要：目的分析复发性泌尿系结石患者的结石成分改变特征及其影响因素。方法回顾性分析深圳市龙岗区人民医院及广东省河源市人民医院2018年1月-2021年5月收治的110例复发性泌尿系结石患者的临床资料,以红外光谱法对其结石成分进行检测,分析其复发前后结石成分总体构成改变情况以及成分改变趋势,对可能影响其结石复发成分改变的相关因素进行单因素分析和多因素Logistic回归分析。结果110例初发性泌尿结石患者中在复发时结石成分为草酸钙的比例有一定下降,结石成为为尿酸、胱氨酸以及感染性的比例有一定上升,差异比较均无统计学意义(P>0.05)。110例患者复发时共计34例(30.91%)患者发生结石成分改变,最常见转变成分的结石为草酸钙结石和感染性结石。单因素分析显示性别、日饮水量以及复发时间和结石复发成分改变存在密切关系(P<0.05),首发年龄、复发次数、初发结石类型以及位置和结石复发成分改变无明显相关(P>0.05)。多因素Logistic回归分析结果显示影响患者结石复发成分改变的独立危险因素为男性和复发时间<1年或者>5年(P<0.05)。结论大约有1/3左右复发性泌尿系结石患者的结石成分会发生改变,其中最常见转变成分的结石为草酸钙结石和感染性结石,影响患者结石复发成分改变的独立危险因素为男性和复发时间<1年或者>5年。Objective To analyze the characteristics and influencing factors of stone composition changes in patients with recurrent urinary stones.Methods To retrospectively analyze the clinical data of 110 patients with recurrent urinary calculi in our hospital and the People’s Hospital of Heyuan City,Guangdong Province from January 2018 to May 2021.The components of the stones were detected by infrared spectroscopy,and their recurrence was analyzed before and after recurrence for the change in the overall composition of the stone composition and the trend of the composition change,the single factor analysis and the multivariate Logistic regression analysis of the related factors that may affect the change of the stone recurrence composition.Results In 110 patients with primary urinary calculi,the proportion of stones as calcium oxalate at recurrence decreased to a certain extent,and the proportion of stones as uric acid,cystine and infectivity increased to a certain extent,and the difference was not statistically significant(P>0.05).A total of 34 patients(30.91%)of 110 patients had changes in the composition of stones when they relapsed.The most common changes in the composition of the stones were calcium oxalate stones and infectious stones.Univariate analysis showed that gender,daily water intake and recurrence time were closely related to changes in stone recurrence components(P<0.05).The age of first episode,number of recurrences,type and location of first stones were not significantly related to changes in stone recurrence components(P>0.05).The results of multivariate Logistic regression analysis showed that the independent risk factors affecting the changes in the components of the patient’s stone recurrence were male and the recurrence time was less than 1 year or more than 5 years (P<0.05). Conclusion About one-third of patients with recurrent urinary tract stones will have changes in the stone composition. The most common conversion stones are calcium oxalate stones and infectious stones. The independent ris

关 键 词：复发 泌尿系结石 结石成分 改变特征 影响因素 

分 类 号：R691.4[医药卫生—泌尿科学]