Study on the anti-inflammatory and analgesic effects of white peony root and mucuna pruriens and their combinations in vivo  

作　　者：Xue-Ying Yu Shi-Bo Zhao Hui-Man Yang Han-Jun Ma Xue-Wei Huang Peng-Yu Deng Shi-You Zhou Suo-Yi Huang 

机构地区：[1]College of Clinical Medicine,Youjiang Medical University for Nationalities,Baise 533000,China [2]College of Pharmacy,Youjiang Medical University for Nationalities,Baise 533000,China [3]Key Laboratory of Guangxi Universities on National Medicine in Youjiang River,Youjiang Medical University for Nationalities,Baise 533000,China

出　　处：《Drug Combination Therapy》2022年第2期1-4,共4页药物联合治疗

基　　金：This work was supported by National Natural Science Foundation of China(No.81360684);Guangxi Key Research and Development Plan Project(Gui Ke AB18221095);Teaching Teacher Training Project from Youjiang Medical University for Nationalities-National Teaching Teacher Training Project(You Hospital Zi[2018]No.98);High-level Talent Research Projects from Youjiang Medical University For Nationalities(No.01002018079);China National and Regional University Students Innovation and Entrepreneurship Training Scheme Funding(No.201910599012);China Regional University Students Innovation and Entrepreneurship Training Scheme Funding(No.202010599072).

摘　　要：Objective:This study investigates the in vivo anti-inflammatory and analgesic pharmacological effects of white peony root and mucuna pruriens and their combinations.Methods:In this study,the corresponding solutions were administered in groups,and after 14 days of gavage,xylene-induced ear swelling test,acetic acid torsion test and hot plate pain test were performed.Results:It was found that both Paeonia lactiflora root and Kapok had anti-inflammatory and analgesic effects(P<0.05),with the 2:1 group having the best experimental effect(P<0.05).Conclusion:Paeonia lactiflora root and Kapok and its combination have good anti-inflammatory and analgesic effects in vivo,and the 2:1 group showed significant anti-inflammatory and analgesic effects compared with other groups.

关 键 词：white peony root PAPAYA aqueous extract anti-inflammatory effect analgesic effect 

分 类 号：TN9[电子电信—信息与通信工程]