基于化腐生肌理论探讨菠萝蛋白酶联合橡皮生肌膏在慢性创面中的应用  

Application of Bromelain Combined with Rubber Shengji Ointment in Chronic Wound Based on Theory of Transforming Putrefaction into Muscle

作　　者：刘婷婷 施悦 孟祥伟 关如东 LIU Tingting;SHI Yue;MENG Xiangwei;GUAN Rudong(Tianjin Binhai New Area Traditional Chinese Medicine Hospital,Tianjin 300450,China)

机构地区：[1]天津市滨海新区中医医院,天津300450

出　　处：《现代中医药》2022年第4期27-31,共5页Modern Chinese Medicine

基　　金：国家重点研发计划项目(2019YFC1709303)。

摘　　要：中医药治疗慢性创面有其独特优势及理论体系,中医外治法之化腐生肌法被历代医家广泛用于外科疮疡治疗。文章基于化腐生肌理论,探讨菠萝蛋白酶联合橡皮生肌膏在慢性创面中的应用。菠萝蛋白酶具有蛋白水解作用,可分解清除创面焦痂、坏死或失活的组织,改善组织微循环状,发挥抗炎作用;橡皮生肌膏通过有效地调节创面组织细胞的功能,从而抗感染和促进组织愈合,两者结合故可能提高创面愈合质量及临床疗效。Traditional Chinese medicine has its unique advantages and theoretical system in the treatment of chronic wounds.The external treatment of traditional Chinese medicine,the method of transforming putrefaction muscle,has been widely used in the treatment of surgical sores by doctors of all dynasties.Based on the theory of transforming putrefaction muscle,this paper discusses the application of bromelain combined with Xiangpi Shengji ointment in chronic wound.Bromelain has the function of protein hydrolysis,which can decompose and remove the eschar,necrotic or inactivated tissue of the wound,improve the tissue microcirculation,and play an anti-inflammatory role;By effectively regulating the function of wound tissue cells,Xiangpi Shengji ointment can resist infection and promote tissue healing.The combination of the two may improve the quality of wound healing and clinical efficacy.

关 键 词：慢性创面 化腐生肌理论 菠萝蛋白酶 橡皮生肌膏 

分 类 号：R285.6[医药卫生—中药学]