高糖代谢记忆引发大血管病变的中医病理探析  

Pathogenesis of diabetic metabolic memory-induced macrovascular disease in traditional Chinese medicine

作　　者：高泓[1] 段玉红 谢红艳[1] 富晓旭[1] 袁海泼[1] 刘桠[1] 冷玉琳 田野 谢子妍 谢春光[1] GAO Hong;DUAN Yuhong;XIE Hongyan;FU Xiaoxu;YUAN Haipo;LIU Ya;LENG Yulin;TIAN Ye;XIE Ziyan;XIE Chunguang(Hospital of Chengdu University of TCM,Chengdu 610072,China;Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang 712000,China)

机构地区：[1]成都中医药大学附属医院,四川成都610072 [2]陕西中医药大学附属医院,陕西咸阳712000

出　　处：《空军军医大学学报》2022年第2期212-214,共3页Journal of Air Force Medical University

基　　金：国家自然科学基金(81774302);四川省科技计划重点研发项目(2019YFS0022);四川省中医药管理局科学技术研究专项(2018KF003,2018JC015)。

摘　　要：代谢记忆是糖尿病大血管防治的关键瓶颈,这使目前西医临床指导方案难以降低大血管病变的致死致残率。我们从中医视角对代谢记忆进行认知:代谢记忆是邪毒销蚀正气的长期过程,脾虚正损是基础,邪蚀正殆是核心,邪毒与正殆二者循环促进,单独解决任何一方均无法打破其交互作用。本文从传统中医理论入手,对糖尿病代谢记忆的发生、发展及大血管损伤作用进行分析,希望能够对临床抑制代谢记忆、阻止大血管损伤进程提供干预思路。Metabolic memory is the key bottleneck in the prevention and treatment of diabetic macrovascular diseases,which makes it difficult to reduce the mortality and disability rate of macrovascular diseases by means of the current clinical guidance programs of western medicine.We recognize metabolic memory from the perspective of traditional Chinese medicine(TCM):metabolic memory is a long-term process of the erosion of pathogenic factor and the exhaustion of healthy qi;spleen deficiency and vital qi damage are the foundation;evil qi erosion and vital qi exhaustion are the core;and the circulation of evil qi erosion and vital qi exhaustion is promoted,and solving either side alone cannot break the interaction.Starting from TCM theories,this paper analyzed the occurrence,development and damage of metabolic memory in diabetes mellitus,hoping to provide intervention ideas for clinical inhibition of metabolic memory and prevention of the process of macrovascular injury.

关 键 词：代谢记忆 糖尿病大血管病变 邪蚀正殆 病机 理论探讨 

分 类 号：R587.1[医药卫生—内分泌]