基于Pentacam和Corvis ST测量近视患者角膜的弹性模量  

Determination of the Elastic Modulus of Cornea of Myopia Patients Based on Pentacam and Corvis ST

作　　者：孟乔宇 王晓君 李晓娜 贺瑞[4] 孟莹 MENG Qiaoyu;WANG Xiaojun;LI Xiaona;HE Rui;MENG Ying(Institute of Advanced Structure Technology,Beijing Institute of Technology,Beijing 100081,China;College of Mechanical and Vehicle Engineering,Taiyuan University of Technology,Taiyuan 030024,China;College of Biomedical Engineering,Taiyuan University of Technology,Taiyuan 030024,China;Department of Excimer Laser,Shanxi Eye Hospital,Taiyuan 030002,China;Institute of Control Engineering,Tianjin Urban Construction University,Tianjin 300384,China)

机构地区：[1]北京理工大学先进结构技术研究院,北京100081 [2]太原理工大学机械与运载工程学院,太原030024 [3]太原理工大学生物医学工程学院,太原030024 [4]山西省眼科医院准分子激光科,太原030002 [5]天津城建大学控制与机械工程学院,天津300384

出　　处：《太原理工大学学报》2022年第4期721-727,共7页Journal of Taiyuan University of Technology

基　　金：国家自然科学基金面上资助项目(11872262);山西省重点研发计划资助项目(201703D421019)。

摘　　要：通过三维眼前节分析仪地形数据建立近视眼角膜几何模型,模拟了可视化角膜生物力学分析仪的检测过程,并与临床实际检测结果进行了对比,逆向求解出20例近视眼角膜弹性模量,弹性模量均值为0.822 MPa±0.146 MPa.根据求解出的近视角膜弹性模量,可为建立近视角膜有限元模型提供一定的参考,以期为后续更准确地模拟角膜屈光手术及预测术后角膜力学性能提供理论基础。The biomechanical properties of the cornea are of great significance to corneal refractive surgery and postoperative corneal deformation,development,and pathology.In this paper,a geometric model of the cornea of myopia was established on the basis of the topographic data of a three-dimensional anterior segment analyzer,and the detection process of the visualized corneal biomechanics analyzer was simulated.Compared with the actual clinical detection results,the corneal elastic modulus and elastic modulus of 20 cases of myopia were calculated inversely.The mean value is 0.822 MPa±0.146 MPa.The calculated elastic modulus of myopia can provide a reference for the establishment of the finite element model of myopia,which is expected to provide a theoretical basis for the subsequent more accurate simulation of corneal refractive surgery and prediction of postoperative corneal mechanical properties.

关 键 词：角膜 生物力学 PENTACAM Corvis ST 有限元模型 

分 类 号：R318.01[医药卫生—生物医学工程]