MeOTf-catalyzed formal[4+2]annulations of styrene oxides with alkynes leading to polysubstituted naphthalenes through sequential electrophilic cyclization/ring expansion  

作　　者：Song Zou Zeyu Zhang Chao Chen Chanjuan Xi 

机构地区：[1]MOE Key Laboratory of Bioorganic Phosphorus Chemistry&Chemical Biology,Department of Chemistry,Tsinghua University,Beijing 100084,China [2]State Key Laboratory of Elemento-Organic Chemistry,Nankai University,Tianjin 300071,China

出　　处：《Chinese Chemical Letters》2022年第6期3021-3025,共5页中国化学快报（英文版）

基　　金：the National Key Research and Development Program of China(No.2016YFB0401400);the National Natural Science Foundation of China(Nos.21871163 and 22071134)。

摘　　要：Me OTf-catalyzed formal[4+2]annulation of styrene oxides with alkynes to afford polysubstituted naphthalenes has been realized,which undergoes sequential electrophilic cyclization/ring expansion.A range of substrates were tolerated in the formation of naphthalene derivatives with high regioselectivity in satisfactory yields.The reaction could also be carried out on gram scale.

关 键 词：Methyltriflate Catalytic reaction ANNULATION Ring expansion Polysubstituted naphthalenes 

分 类 号：O625.151[理学—有机化学]