冠状动脉旁路移植术后静脉旁路移植血管再狭窄的早期机制、预测、预防研究进展  

The mechanism,prediction,and prevention of saphenous vein grafts stenosis in early stage

作　　者：杨耀辰 董然[1] Yang Yaochen;Dong Ran(Department of Cardiac Surgery,Beijing Anzhen Hospital,Capital University of Medical Sciences,Beijing 100029,China)

机构地区：[1]首都医科大学附属北京安贞医院心脏外科,北京100029

出　　处：《中华胸心血管外科杂志》2022年第6期376-379,共4页Chinese Journal of Thoracic and Cardiovascular Surgery

基　　金：国家自然科学基金(81770412)。

摘　　要：目前,冠状动脉旁路移植术仍是治疗冠心病(尤其是严重冠状动脉多支狭窄病变)的首选治疗方法之一。可用于CABG术的旁路移植血管选择多样,其中大隐静脉因获取难度低、长度足够、对获取位置肢体血供影响小的特点,成为术中最常用的旁路移植血管。然而,相对于动脉旁路移植血管,大隐静脉远期通畅率低,存在更多致管腔狭窄因素。内膜损伤、急性血栓形成和平滑肌细胞增生是早期血管再狭窄的风险因素,也为远期狭窄奠定了基础。本文对CABG术后大隐静脉再狭窄早期机制、预测及预防的最新研究进展作简要综述。Coronary artery bypass grafting is one of preferred therapy of coronary artery diseases,especially in severe coronary arteries stenosis.Grafts for CABG are optional,but the most used of graft is still saphenous vein,which has characteristics in convenience of harvesting,sufficient of length,and minimal affection of blood supply.Comparing with arterial grafts,pro-stenosis factors in saphenous vein graft are more like expressing.In early stage of stenosis of saphenous vein graft,intimal injury,acute thrombogenesis,and hyperplasia of venous smooth muscle cells,are risk factors which also influence long stage of stenosis.The article aimed to briefly illustrate mechanism,prediction,and prevention in early stage of SVG stenosis.

关 键 词：血管再狭窄 平滑肌细胞增生 大隐静脉 远期通畅率 内膜损伤 动脉旁路移植 冠状动脉旁路移植术 急性血栓形成 

分 类 号：R654.2[医药卫生—外科学]