基于病原体检验与基于宿主反应检验的联合应用  

Combined application of pathogen-based tests and host reaction-based tests

作　　者：叶青[1] 尚世强[1] Qing Ye;Shiqiang Shang(Department of Clinical Laboratory,the Children′s Hospital,Zhejiang University School of Medicine,National Clinical Research Center for Child Health,National Children′s Regional Medical Center,Hangzhou 310052,China)

机构地区：[1]浙江大学医学院附属儿童医院实验检验中心,国家儿童健康与疾病临床医学研究中心,国家儿童区域医疗中心,杭州310052

出　　处：《中华检验医学杂志》2022年第6期559-562,共4页Chinese Journal of Laboratory Medicine

摘　　要：感染性疾病的发生和进展涉及病原体和宿主的免疫反应这两个方面。目前基于病原体的检验是感染性疾病诊断的金标准和最常用的方法。免疫系统的功能是识别和消除入侵的病原体,基于宿主反应的检验已成为传统的基于病原体检验的有效辅助手段,具有提高诊断准确性和效率的潜力。基于宿主的检验与基于病原体的检验的联合应用是一个值得探索的新领域。The occurrence development and progression of infectious diseases involves the two aspects:the immune response of both the pathogens and the hosts.At present,pathogen-based testing is the gold standard and the most commonly used method for the diagnosis of infectious diseases.The purpose of the immune system is to identify and eliminate invading pathogens.Testing based on host reactions has become an effective auxiliary means adjunct of traditional pathogen-based tests,with the potential to improve the accuracy and efficiency of diagnosis.The combined application of host-based tests and pathogen-based tests is a new field worth exploring.

关 键 词：诊断 宿主 病原体 生物标志物 

分 类 号：R446.5[医药卫生—诊断学]