Genomic footprints of sorghum domestication and breeding selection for multiple end uses  

作　　者：Xiaoyuan Wu Yuanming Liu Hong Luo Li Shang Chuanyuan Leng Zhiquan Liu Zhigang Li Xiaochun Lu Hongwei Cai Huaiqing Hao Hai-Chun Jing 

机构地区：[1]Key Laboratory of Plant Resources,Institute of Botany,Chinese Academy of Sciences,Beijing 100093,China [2]Engineering Laboratory for Grass-Based Livestock Husbandry,Institute of Botany,Chinese Academy of Sciences,Beijing 100093,China [3]University of Chinese Academy of Sciences,Beijing 100049,China [4]College of Grassland Science and Technology,China Agricultural University,Beijing 100193,China [5]Institute of Sorghum Research,Liaoning Academy of Agricultural Sciences,Shenyang 110161,China

出　　处：《Molecular Plant》2022年第3期537-551,共15页分子植物（英文版）

基　　金：This research was supported by the National Key R&D Program of China(2018YFD1000701 and 2019YFD1002701);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA26050101).

摘　　要：Domestication and diversification have had profound effects on crop genomes.Originating in Africa and subsequently spreading to different continents,sorghum(Sorghum bicolor)has experienced multiple onsets of domestication and intensive breeding selection for various end uses.However,how these processes have shaped sorghum genomes is not fully understood.In the present study,population genomics analyses were performed on a worldwide collection of 445 sorghum accessions,covering wild sorghum and four end-use subpopulations with diverse agronomic traits.Frequent genetic exchanges were found among various subpopulations,and strong selective sweeps affected 14.68%(∼107.5 Mb)of the sorghum genome,including 3649,4287,and 3888 genes during sorghum domestication,improvement of grain sorghum,and improvement of sweet sorghum,respectively.Eight different models of haplotype changes in domestication genes from wild sorghum to landraces and improved sorghum were observed,and Sh1-and SbTB1-type genes were representative of two prominent models,one of soft selection or multiple origins and one of hard selection or an early single domestication event.We also demonstrated that the Dry gene,which regulates stem juiciness,was unconsciously selected during the improvement of grain sorghum.Taken together,these findings provide new genomic insights into sorghum domestication and breeding selection,and will facilitate further dissection of the domestication and molecular breeding of sorghum.

关 键 词：sorghum(Sorghum bicolor) genomic footprints end uses domestication and diversification genes SbTB1 Sh1 and Dry molecular breeding 

分 类 号：S336[农业科学—作物遗传育种]