血细胞对4型心肾综合征患者病情和生存质量的影响  

Effect of Blood Cells on Condition and Quality of Life in Patients with Type 4 Cardiorenal Syndrome

作　　者：杨文勇 李明钥 李宪[1] 唐维 Yang Wen-yong;Li Ming-yao;Li Xian;Tang Wei(Jilin Chemical Hospital(the Second Affiliated Hospital of Beihua University),Jilin 132021,Jilin Province,China)

机构地区：[1]吉林市化工医院(北华大学第二附属医院),吉林吉林132021

出　　处：《中国社区医师》2022年第19期73-75,共3页Chinese Community Doctors

基　　金：吉林市医疗卫生指导性计划项目(项目编号:201900979,2021001306,2021001307,2021001310)。

摘　　要：目的:分析血细胞对4型心肾综合征(CRS)患者病情和生存质量的影响。方法:选取2015年1月-2018年12月吉林市化工医院收治的89例4型CRS患者为研究对象,分为慢性肾脏病(CKD)4期组与CKD 5期组。对89例4型心肾综合征患者进行心脏、肾脏检查和血液有形成分检查。分析4型CRS患者有形成分特点和影响因素。比较两组患者的血液有形成分各指标情况、Spearman与生存质量总分及各维度得分的相关性,采用逐步回归分析法分析与生存质量总分相关性。结果:CKD 5期组患者的红细胞压积(HCT)水平高于CKD 4期组,白细胞(WBC)、中性粒细胞计数、红细胞(RBC)、血红蛋白(Hb)水平则低于CKD 4期组,差异有统计学意义(P<0.05)。两组患者的淋巴细胞计数、单核细胞计数、血小板计数水平比较,差异无统计学意义(P>0.05)。Hb、RBC、HCT与患者生存质量总分、生理、心理维度得分呈负相关。WBC、Hb、RBC与患者生存质量偏回归系数有意义,差异有统计学意义(P<0.05),WBC、Hb、RBC与4型CRS生存质量呈正相关。结论:血液有形成分对4型CRS患者的病情、生存质量均存在一定的影响。Objective:To analyze the effect of blood cells on the condition and quality of life of patients with type 4 cardiorenal syndrome(CRS).Methods:A total of 89 patients with type 4 CRS who were admitted to Jilin Chemical Hospital from January 2015 to December 2018 were selected as the study subjects and they were divided into chronic kidney disease(CKD)stage 4 group and CKD stage 5 group.The 89 patients with type 4 CRS were examined for heart,kidney and blood formed element.The characteristics and influencing factors of the formed elements of patients with type 4 CRS were analyzed.The indexes of blood formed element,the correlations of Spearman with total score of quality of life and each dimension score were compared between the two groups,and the correlation with the total score of quality of life was analyzed by stepwise regression analysis.Results:The hematocrit(HCT)level of the patients in the CKD stage 5 group was higher than that in the CKD stage 4 group,while the white blood cell(WBC),neutrophil count,red blood cell(RBC),and hemoglobin(Hb)levels were lower than those in the CKD stage 4 group,with statistically significant difference(P<0.05).There was no significant difference in lymphocyte count,monocyte count and platelet count between the two groups(P>0.05).Hb,RBC and HCT were negatively correlated with the total score of quality of life,physical and psychological dimensions of patients.The WBC,Hb,RBC were associated with the partial regression coefficient of the quality of life of patients,and the difference was statistically significant(P<0.05).WBC,Hb,RBC were positively correlated with the quality of life of type 4 CRS.Conclusion:The blood formed elements have a certain influence on the condition and quality of life of patients with type 4 CRS.

关 键 词：逐步回归法 心肾综合征 贫血 心力衰竭 心功能 

分 类 号：R541.6[医药卫生—心血管疾病]