药品中抗生素含量检测方法研究进展  

Advances in the detection of antibiotics in drugs

作　　者：田新岳 马春芳 张雯 吴春燕 邵倩 崔生玲 杨奇 余永涛[1] Tian Xinyue;Ma Chunfang;Zhang Wen;Wu Chunyan;Shao Qian;Cui Shengling;Yang Qi;Yu Yongtao(School of Agriculture,Ningxia University,Yinchuan 750021,China;Ningxia Veterinary Medicine and Feed Supervision Institute,Yinchuan 750004,China)

机构地区：[1]宁夏大学农学院,宁夏银川750021 [2]宁夏兽药饲料监察所,宁夏银川750004

出　　处：《农业科学研究》2022年第2期55-60,共6页Journal of Agricultural Sciences

基　　金：农业行业(国家)标准项目(HY-2020-09);国家自然科学基金项目(31560713,31960348)。

摘　　要：药品中抗生素含量的测定是确保抗生素类药物有效性和减少抗生素滥用的一项十分重要的技术。抗生素含量的测定方法主要包括生物测定法、紫外-可见分光光度法和高效液相色谱法。本文对近年来抗生素含量检测方法的研究和应用进行综述,旨在为抗生素类药物的质量控制和研究应用提供参考。It is a very important technical guarantee of the determination of antibiotic content in drugs to ensure the effectiveness of antibiotics and reduce the abuse of antibiotics.Drug residues as a new kind of organic pollutants are attracting more and more attention,so the determination of antibiotic content is particularly important.The main determination methods of antibiotic content include biometric method,ultraviolet spectrophotometer method and liquid chromatography method.In this paper,the research and application of antibiotic content detection methods in recent years are reviewed to provide ideas and knowledge for the quality control and research application of antibiotic drugs.

关 键 词：抗生素 含量检测 抗生素微生物检定法 高效液相色谱法 紫外-可见分光光度法 

分 类 号：R927.1[医药卫生—药学]