脑心同治法治疗帕金森病睡眠障碍临床观察  

Clinical Observarion on Simultaneous Treatment of Brain and Heart in the Treatment of Sleep Disorders of Parkinson’s Disease

作　　者：许雪梅[1] 万蝉俊[1] 王慧萍[1] 丁聪 邓红[1] 曹文博 XU Xuemei;WAN Chanjun;WANG Huiping;DING Cong;DENG Hong;CAO Wenbo(Department of Neurosurgery,Affiliated Hospital of Jiangxi University of Chinese Medicine,Jiangxi Province,Nanchang 330006,China)

机构地区：[1]江西中医药大学附属医院神经外科,江西南昌330006

出　　处：《中国中医药现代远程教育》2022年第14期95-97,共3页Chinese Medicine Modern Distance Education of China

基　　金：江西省卫生健康委中医药科研项目【No.2018A072,2018A007,2016A132】;江西省卫生健康委科技计划项目【No.20203433,20203423】。

摘　　要：目的观察脑心同治法治疗气血亏虚型帕金森病睡眠障碍患者的临床疗效。方法将2018年1月—2019年12月江西中医药大学附属医院收治的64例失眠患者随机分为对照组和观察组,各32例。对照组采用帕金森常规西药和右佐匹克隆治疗,观察组在对照组基础上加用十味温胆汤化裁治疗,疗程均为4周。观察治疗后患者的临床总有效率、中医证候积分及帕金森睡眠量表(PDSS)评分。结果治疗前,2组中医证候积分、PDSS评分比较,差异无统计学意义(P>0.05);治疗后,观察组临床总有效率87.5%(28/32)明显高于对照组62.5%(20/32),差异有统计学意义(P<0.05)。观察组PDSS评分、中医证候积分疗效均明显优于对照组,差异有统计学意义(P<0.05)。结论脑心同治对气血不足型帕金森睡眠障碍疗效确切,可以明显改善患者的临床症状和睡眠质量,安全有效。Objective To explore the effect of simultaneous treatment of brain and heart on sleep disorders of Parkinson’s disease of deficiency of qi and blood type.Methods Totally 64 patients with Parkinson’s disease insomnia in Affiliated Hospital of Jiangxi University of Chinese Medicine from January 2018 to December 2019 were divided into control group and observation group by random number method,with 32 cases in each group.The control group were given regular western medicine and right zopiclone tablets treatment.The observation group were additionally given Shiwei Wendan decoction.The treatment course was 8 weeks.The clinical efficacy,traditional Chinese medicine(TCM)syndrome score and PDSS score were observed.Results Before treatment,there was no significant difference in TCM syndrome score and PDSS score between 2 groups(P>0.05).After treatment,the total clinical effective rate of the observation group(87.5%,28/32)was significantly higher than that of the control group(62.5%,20/32),and the difference was statistically significant(P<0.05).The PDSS score and TCM syndrome score of the observation group were significantly better than those of the control group,and the difference had statistical significance(P<0.05).Conclusion The therapeutic effect of simultaneous treatment of brain and heart on sleep disorder of Parkinson’s disease with deficiency of qi and blood is definite,which can obviously improve the clinical symptoms and sleep quality of the patients,and it is safe and effective.

关 键 词：脑心同治 中医药 帕金森病 睡眠障碍 

分 类 号：R277.7[医药卫生—中医学]