超声引导下粗针穿刺活检诊断淋巴瘤的临床价值  

Clinical value of ultrasound guide core needle biopsy in the diagnosis of lymphoma

作　　者：何玲 彭钰蓓 寇震 马可欣 刘丽萍[1] HE Ling;PENG Yupei;KOU Zhen;MA Kexin;LIU Liping(Department of Ultrasound,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400042,China)

机构地区：[1]重庆医科大学附属第一医院超声科,重庆市400042

出　　处：《临床超声医学杂志》2022年第7期545-548,共4页Journal of Clinical Ultrasound in Medicine

摘　　要：目的探讨超声引导下粗针穿刺活检(USG-CNB)在淋巴瘤诊断中的临床应用价值。方法回顾性分析于我院行USG-CNB和手术切除活检(SEB)的淋巴瘤患者353例,根据取材方法分为USG-CNB组139例和SEB组214例。除4例为临床诊断外,其余349例均获明确病理诊断。比较USG-CNB与SEB对淋巴瘤首次取材的诊断准确率,以及二者对霍奇金淋巴瘤(HL)与非霍奇金淋巴瘤(NHL)、不同部位NHL的诊断效能;比较USG-CNB对不同大小淋巴瘤的诊断效能。结果USG-CNB组首次取材确诊117例,SEB组首次取材确诊202例,两组首次取材诊断准确率比较(84.2%vs.94.4%),差异有统计学意义(P=0.003)。USG-CNB与SEB对HL的诊断准确率比较(50.0%vs.100%),差异有统计学意义(P<0.001);对NHL的诊断准确率比较(88.6%vs.93.8%),差异无统计学意义。USG-CNB与SEB对浅表淋巴瘤的诊断准确率比较(83.0%vs.93.5%),差异有统计学意义(P=0.001);对深部淋巴瘤的诊断准确率比较(87.9%vs.96.6%),差异无统计学意义。USG-CNB与SEB对浅表与深部NHL的诊断准确率比较差异均无统计学意义。USG-CNB对不同大小淋巴瘤病灶的诊断准确率比较差异均无统计学意义。结论应用USG-CNB诊断淋巴瘤具有实时、快速、微创、价廉等优势,尤其对位于深部的淋巴瘤病灶的诊断价值较高。Objective To explore the clinical application value of ultrasound guide core needle biopsy(USG-CNB)in the diagnosis of lymphoma.Methods The clinical data of 353 patients with lymphoma who underwent USG-CNB and surgical excision biopsy(SEB)in our hospital were analyzed retrospectively.They were divided into 139 cases in the USG-CNB group and 214 cases in the SEB group.Except for 4 cases confirmed by clinical diagnosis,the other 349 cases were confirmed by pathological diagnosis.The following items were compared and analyzed:the diagnostic accuracy of USG-CNB and SEB in lymphoma by first sampling,the diagnostic efficacy of USG-CNB and SEB in Hodgkin’s lymphoma(HL)and non-Hodgkin’s Lymphoma(NHL),the diagnostic efficacy of USG-CNB and SEB in different location of NHL,the diagnostic efficacy of USG-CNB in different size of lymphoma.Results The diagnosis was successful in 117 cases in the USG-CNB group and 202 cases in the SEB group by first sampling,and the diagnostic accuracy between the two groups was statistically significant(84.2%vs.94.4%,P=0.003).The diagnostic accuracy of USG-CNB and SEB in HL was statistically significant(50.0%vs.100%,P<0.001).There was no significant difference in the diagnostic accuracy of NHL(88.6%vs.93.8%).There was significant difference in the diagnostic accuracy of superficial lymphoma between USG-CNB and SEB(83.0%vs.93.5%,P=0.001).There was no significant difference in the diagnostic accuracy of deep lymphoma between USG-CNB and SEB(87.9%vs.96.6%).There was no significant difference in the diagnostic accuracy of superficial and deep NHL between USG-CNB and SEB.There was no significant difference in the diagnostic accuracy of lymphoma with different size by USG-CNB.Conclusion The application of USG-CNB in the diagnosis of lymphoma has the advantages of real-time,rapid,minimally invasive and cheap,especially for lymphoma lesions located in the deep part.

关 键 词：超声引导 粗针穿刺活检 手术切除活检 淋巴瘤 

分 类 号：R445.1[医药卫生—影像医学与核医学] R733.4[医药卫生—诊断学]