血小板微粒在APS中的研究进展  

The research of platelet microparticles in APS

作　　者：邸龙江 张文静[1] 查才军 刘彦虹[1] Di Longjiang;Zhang Wenjing;Zha Caijun;Liu Yanhong(Department of Clinical Laboratory,the Second Affiliated Hospital of Harbin Medical University,Harbin 150086,China)

机构地区：[1]哈尔滨医科大学附属第二医院检验科,哈尔滨150086

出　　处：《国际免疫学杂志》2022年第2期176-179,共4页International Journal of Immunology

基　　金：国家自然科学基金(82001715)。

摘　　要：抗磷脂综合征(antiphospholipid syndrome,APS)是一种以血管内血栓形成、复发性流产为表现的自身免疫性疾病。近年来,对于APS发病机制的研究有了很大的进展。然而,仍有许多问题没有得到解答。血小板微粒是血小板受到刺激后释放到胞外的一种超微膜性囊泡,它与APS的血栓形成及复发性流产密切相关。文章对血小板微粒在APS中的重要作用作一综述。Antiphospholipid syndrome(APS)is an autoimmune disease characterized by intravascular thrombosis and recurrent abortion.In recent years,great progress has been made in understanding the pathogenesis of antiphospholipid syndrome.However,many questions remain unanswered.Platelet microparticle is a kind of ultramicro membranous vesicle released from platelets after stimulation.It is closely related to thrombosis and recurrent abortion of antiphospholipid syndrome.Therefore,the important role of platelet microparticle in antiphospholipid syndrome was reviewed.

关 键 词：抗磷脂综合征 血小板微粒 血栓形成 

分 类 号：R593.2[医药卫生—内科学]