围手术期血糖监测指标的研究进展  

Research progress on perioperative glucose monitoring indicators

作　　者：张笑婷 王少康 薄禄龙 邓小明 Zhang Xiaoting;Wang Shaokang;Bo Lulong;Deng Xiaoming(Faculty of Anesthesiology,the First Affiliated Hospital of Naval Military Medical University,Shanghai 200433,China;Department of Emergency,the First Affiliated Hospital of Naval Military Medical University,Shanghai 200433,China)

机构地区：[1]海军军医大学第一附属医院麻醉学部,上海200433 [2]海军军医大学第一附属医院急诊科,上海200433

出　　处：《国际麻醉学与复苏杂志》2022年第4期406-409,共4页International Journal of Anesthesiology and Resuscitation

基　　金：上海市青年科技启明星计划(19QA1408500)。

摘　　要：糖尿病及高血糖是导致不良手术结局的重要危险因素。随着加速康复外科理念的不断发展, 优化围手术期血糖水平成为麻醉医师与外科医师的共同目标。文章回顾传统血糖监测指标[糖化血红蛋白(glycated hemoglobin A1c, HbA1c)、血糖]围手术期应用的局限, 介绍新兴血糖监测指标[果糖胺(fructosamine, FA)、糖化白蛋白(glycosylated albumin, GA)和1, 5-脱水葡萄糖醇(1, 5-anhydroglucitol, 1, 5-AG)等]的定义及临床应用, 探讨新兴血糖监测指标在识别高危患者并改善术前优化中的作用, 评估其在降低术后并发症发生率中的价值。麻醉医师、外科医师和内分泌科医师应加强多学科协作, 推动针对新兴血糖监测指标相关研究的不断深入, 为改善患者围手术期管理作出贡献。Diabetes and hyperglycemia are important risk factors which may result in adverse surgical outcomes.With the de⁃velopment of enhanced recovery after surgery,management of perioperative glucose level becomes the common goal of both anesthesiol⁃ogists and surgeons.This review illustrated the limitations of the perioperative application of traditional glucose monitoring indicators,such as glycated hemoglobin A1c(HbA1c)and blood glucose.It introduced the definition and clinical application of emerging glucose monitoring indicators,including fructosamine(FA),glycosylated albumin(GA),and 1,5⁃anhydroglucitol(1,5⁃AG),discussed the role of emerging blood glucose monitoring indicators in identifying high⁃risk patients and improving preoperative optimization,and evaluat⁃ed its value in reducing the incidence of postoperative complications.Anesthesiologists,surgeons,and endocrinologists should strength⁃en multidisciplinary cooperation,promote the continuous deepening of research on emerging blood glucose monitoring indicators,and contribute to improving perioperative management of patients.

关 键 词：糖尿病 高血糖症 糖化血红蛋白 果糖胺 糖化白蛋白 1 5-脱水葡萄糖醇 

分 类 号：R614[医药卫生—麻醉学]